Noma (cancrum oris): An unresolved global challenge.
Journal
Periodontology 2000
ISSN: 1600-0757
Titre abrégé: Periodontol 2000
Pays: Denmark
ID NLM: 9313276
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
entrez:
16
5
2019
pubmed:
16
5
2019
medline:
27
11
2019
Statut:
ppublish
Résumé
Noma (canrum oris) is a mutilating necrotizing disease of uncertain etiology, but it is accepted that it is caused primarily by a polybacterial infection with secondary ischemia. The consequent necrotizing fasciitis, myonecrosis, and osteonecrosis results in destruction of facial structures with severe functional impairment and disfigurement. It most frequently affects children, particularly in sub-Saharan Africa, who are malnourished or debilitated by systemic conditions including but not limited to malaria, measles, and tuberculosis; and less frequently debilitated HIV-seropositive subjects. In the vast majority of cases, in susceptible subjects, noma is preceded by necrotizing stomatitis. However, it has been reported, albeit rarely, that noma can arise without any preceding oral lesions being observed. Noma is not recurrent and is not transmissible.
Identifiants
pubmed: 31090145
doi: 10.1111/prd.12275
pmc: PMC7328761
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
189-199Informations de copyright
© 2019 The Authors. Periodontology 2000 Published by John Wiley & Sons Ltd.
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