Use of trypan blue as an aqueous tracer dye to investigate hypotony where cyclodialysis cleft is suspected.
Aged
Aged, 80 and over
Anterior Chamber
/ drug effects
Aqueous Humor
/ physiology
Coloring Agents
/ administration & dosage
Cyclodialysis Clefts
/ diagnosis
Female
Gonioscopy
Humans
Injections, Intraocular
Intraocular Pressure
/ physiology
Male
Ocular Hypotension
/ diagnosis
Prospective Studies
Tertiary Care Centers
Tonometry, Ocular
Trypan Blue
/ administration & dosage
Visual Acuity
/ physiology
blunt trauma
cyclodialysis cleft
diagnostic technique
hypotony
trabeculectomy
Journal
Clinical & experimental ophthalmology
ISSN: 1442-9071
Titre abrégé: Clin Exp Ophthalmol
Pays: Australia
ID NLM: 100896531
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
22
12
2018
revised:
23
04
2019
accepted:
23
04
2019
pubmed:
16
5
2019
medline:
21
10
2020
entrez:
16
5
2019
Statut:
ppublish
Résumé
A new method to help diagnose suspected cyclodialysis clefts. To study the use of trypan blue stained aqueous flow patterns in diagnosing causes of hypotony where cyclodialysis clefts were suspected. A case series in a tertiary care centre. Ten subjects presenting with persistent hypotony and retinal changes. Trypan blue was injected into the anterior chamber. The pattern of dye flow in the anterior chamber was categorized. Intraocular pressure prior to surgery was recorded. All seven subjects with cyclodialysis clefts had a preferential flow to the cleft region. Two hypotonous subjects post trabeculectomy had rapid (5 seconds) and extensive lymphatic staining (6 o'clock hours extent) without visible bleb formation. Preferential flow of dye to the limbus is a reliable sign of cyclodialysis cleft and helps localize cleft extent. A new cause of hypotony, "lymphatic overdrain," is identified.
Sections du résumé
IMPORTANCE
OBJECTIVE
A new method to help diagnose suspected cyclodialysis clefts.
BACKGROUND
BACKGROUND
To study the use of trypan blue stained aqueous flow patterns in diagnosing causes of hypotony where cyclodialysis clefts were suspected.
DESIGN
METHODS
A case series in a tertiary care centre.
PARTICIPANTS
METHODS
Ten subjects presenting with persistent hypotony and retinal changes.
METHODS
METHODS
Trypan blue was injected into the anterior chamber.
MAIN OUTCOME MEASURES
METHODS
The pattern of dye flow in the anterior chamber was categorized. Intraocular pressure prior to surgery was recorded.
RESULTS
RESULTS
All seven subjects with cyclodialysis clefts had a preferential flow to the cleft region. Two hypotonous subjects post trabeculectomy had rapid (5 seconds) and extensive lymphatic staining (6 o'clock hours extent) without visible bleb formation.
CONCLUSIONS AND RELEVANCE
CONCLUSIONS
Preferential flow of dye to the limbus is a reliable sign of cyclodialysis cleft and helps localize cleft extent. A new cause of hypotony, "lymphatic overdrain," is identified.
Substances chimiques
Coloring Agents
0
Trypan Blue
I2ZWO3LS3M
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
904-908Subventions
Organisme : National Health and Medical Research Council
ID : 107310
Organisme : National Health and Medical Research Council
ID : 102367
Informations de copyright
© 2019 Royal Australian and New Zealand College of Ophthalmologists.
Références
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