Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
06 2019
Historique:
received: 13 09 2018
accepted: 10 04 2019
pubmed: 17 5 2019
medline: 15 2 2020
entrez: 17 5 2019
Statut: ppublish

Résumé

HIV/AIDS is a leading cause of disease burden in sub-Saharan Africa. Existing evidence has demonstrated that there is substantial local variation in the prevalence of HIV; however, subnational variation has not been investigated at a high spatial resolution across the continent. Here we explore within-country variation at a 5 × 5-km resolution in sub-Saharan Africa by estimating the prevalence of HIV among adults (aged 15-49 years) and the corresponding number of people living with HIV from 2000 to 2017. Our analysis reveals substantial within-country variation in the prevalence of HIV throughout sub-Saharan Africa and local differences in both the direction and rate of change in HIV prevalence between 2000 and 2017, highlighting the degree to which important local differences are masked when examining trends at the country level. These fine-scale estimates of HIV prevalence across space and time provide an important tool for precisely targeting the interventions that are necessary to bringing HIV infections under control in sub-Saharan Africa.

Identifiants

pubmed: 31092927
doi: 10.1038/s41586-019-1200-9
pii: 10.1038/s41586-019-1200-9
pmc: PMC6601349
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

189-193

Subventions

Organisme : Medical Research Council
ID : MR/R015600/1
Pays : United Kingdom
Organisme : NIAID NIH HHS
ID : R03 AI125001
Pays : United States

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Auteurs

Laura Dwyer-Lindgren (L)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Michael A Cork (MA)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Amber Sligar (A)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Krista M Steuben (KM)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Kate F Wilson (KF)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Naomi R Provost (NR)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Benjamin K Mayala (BK)

DHS program, ICF International, Rockville, MD, USA.

John D VanderHeide (JD)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Michael L Collison (ML)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Jason B Hall (JB)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Molly H Biehl (MH)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Austin Carter (A)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Tahvi Frank (T)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Dirk Douwes-Schultz (D)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Roy Burstein (R)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Daniel C Casey (DC)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Aniruddha Deshpande (A)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Lucas Earl (L)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Charbel El Bcheraoui (C)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Tamer H Farag (TH)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Nathaniel J Henry (NJ)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Damaris Kinyoki (D)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Laurie B Marczak (LB)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Molly R Nixon (MR)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Aaron Osgood-Zimmerman (A)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

David Pigott (D)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Robert C Reiner (RC)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Jennifer M Ross (JM)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Department of Global Health, University of Washington, Seattle, WA, USA.
Department of Medicine, University of Washington, Seattle, WA, USA.

Lauren E Schaeffer (LE)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

David L Smith (DL)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Nicole Davis Weaver (N)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Kirsten E Wiens (KE)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Jeffrey W Eaton (JW)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Department of Infectious Disease Epidemiology, Imperial College London, London, UK.

Jessica E Justman (JE)

ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.
Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.

Alex Opio (A)

Medireal Investment Uganda, Entebbe, Uganda.

Benn Sartorius (B)

Public Health Medicine, School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Frank Tanser (F)

School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Africa Health Research Institute, KwaZulu-Natal, South Africa.
Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.
Research Department of Infection & Population Health, University College London, London, UK.

Njeri Wabiri (N)

HIV/AIDS, STIs & TB Research Programme, Human Sciences Research Council, Pretoria, South Africa.

Peter Piot (P)

London School of Hygiene & Tropical Medicine, London, UK.

Christopher J L Murray (CJL)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Simon I Hay (SI)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA. sihay@uw.edu.

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Classifications MeSH