The upper level: examining the risk of excess micronutrient intake in pregnancy from antenatal supplements.


Journal

Annals of the New York Academy of Sciences
ISSN: 1749-6632
Titre abrégé: Ann N Y Acad Sci
Pays: United States
ID NLM: 7506858

Informations de publication

Date de publication:
05 2019
Historique:
received: 04 01 2019
revised: 22 03 2019
accepted: 28 03 2019
pubmed: 17 5 2019
medline: 3 4 2020
entrez: 17 5 2019
Statut: ppublish

Résumé

Micronutrient deficiencies are prevalent and co-occurring among pregnant women in low- and middle-income countries (LMIC). To prevent and treat deficiencies, antenatal vitamin and mineral supplements are the most common interventions during gestation. With most micronutrients, there can be health risks when intake regularly exceeds a high amount, and an upper threshold value set by the United States and Canada, the World Health Organization, and other groups is commonly called an upper intake level (UL). This review summarizes what is known about risks in pregnancy when ULs are exceeded and assesses the potential risk of exceeding the UL if a pregnant woman is taking a multiple micronutrient supplement. Overall, there is limited information on pregnancy-specific risks from excess intake. When assuming high dietary intake plus the amount in a standard multiple micronutrient supplement (with 30 mg of iron), only niacin and iron would be expected to slightly exceed the UL. Known risks for this level intake for each nutrient are transient and mild.

Identifiants

pubmed: 31094004
doi: 10.1111/nyas.14103
pmc: PMC6618111
doi:

Substances chimiques

Micronutrients 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

22-34

Subventions

Organisme : Bill & Melinda Gates Foundation
Pays : United States

Informations de copyright

© 2019 The Authors. Annals of the New York Academy of Sciences published by Wiley Periodicals, Inc. on behalf of New York Academy of Sciences.

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Auteurs

Alison D Gernand (AD)

Department of Nutritional Sciences, the Pennsylvania State University, University Park, Pennsylvania.

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Classifications MeSH