Short regimen of rituximab plus lenalidomide in follicular lymphoma patients in need of first-line therapy.


Journal

Blood
ISSN: 1528-0020
Titre abrégé: Blood
Pays: United States
ID NLM: 7603509

Informations de publication

Date de publication:
25 07 2019
Historique:
received: 11 10 2018
accepted: 03 04 2019
pubmed: 19 5 2019
medline: 15 1 2020
entrez: 19 5 2019
Statut: ppublish

Résumé

The SAKK 35/10 phase 2 trial, developed by the Swiss Group for Clinical Cancer Research and the Nordic Lymphoma Group, compared the activity of rituximab vs rituximab plus lenalidomide in untreated follicular lymphoma patients in need of systemic therapy. Patients were randomized to rituximab (375 mg/m

Identifiants

pubmed: 31101627
pii: S0006-4971(20)42383-3
doi: 10.1182/blood-2018-10-879643
doi:

Substances chimiques

Rituximab 4F4X42SYQ6
Lenalidomide F0P408N6V4

Banques de données

ClinicalTrials.gov
['NCT01307605']

Types de publication

Clinical Trial, Phase II Journal Article Multicenter Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

353-362

Informations de copyright

© 2019 by The American Society of Hematology.

Auteurs

Emanuele Zucca (E)

Division of Medical Oncology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
Institute of Oncology Research, Bellinzona, Switzerland.
Department of Medical Oncology, Inselspital/Bern University Hospital, Bern, Switzerland.

Stephanie Rondeau (S)

SAKK Coordinating Center, Bern, Switzerland.

Anna Vanazzi (A)

Clinical Hemato-Oncology, European Institute of Oncology IRCCS, Milan, Italy.

Bjørn Østenstad (B)

Department of Oncology, Oslo University Hospital, Oslo, Norway.

Ulrich J M Mey (UJM)

Medical Oncology and Hematology, Kantonsspital Graubünden, Chur, Switzerland.

Daniel Rauch (D)

Division of Oncology, Spital Thun Simmenthal, Thun, Switzerland.

Björn E Wahlin (BE)

Unit of Hematology, Department of Medicine at Huddinge, Karolinska Institutet, Stockholm, Sweden.

Felicitas Hitz (F)

Oncology/Hematology, Kantonsspital St Gallen, St Gallen, Switzerland.

Micaela Hernberg (M)

Department of Oncology, Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland.

Ann-Sofie Johansson (AS)

Department of Oncology, Norrlands Universitetssjukhus, Umeå, Sweden.

Peter de Nully Brown (P)

Department of Hematology, Rigshospitalet, Copenhagen, Denmark.

Hans Hagberg (H)

Oncology, Uppsala University Hospital, Uppsala, Sweden.

Andrés J M Ferreri (AJM)

Unit of Lymphoid Malignancies, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Andreas Lohri (A)

Department of Oncology/Hematology, Medical University Clinic, Liestal, Switzerland.

Urban Novak (U)

Department of Medical Oncology, Inselspital/Bern University Hospital, Bern, Switzerland.

Thilo Zander (T)

Department of Oncology, Luzerner Kantonsspital, Luzern, Switzerland.

Hanne Bersvendsen (H)

Department of Oncology, University Hospital of North Norway, Tromsø, Norway.

Mario Bargetzi (M)

Division of Hematology/Oncology, Kantonsspital Aarau, Aarau, Switzerland.

Walter Mingrone (W)

Department of Medical Oncology, Kantonsspital Olten, Olten, Switzerland; and.

Stefan Dirnhofer (S)

Institute of Pathology, University Hospital Basel, Basel, Switzerland.

Stefanie Hayoz (S)

SAKK Coordinating Center, Bern, Switzerland.

Hanne Hawle (H)

SAKK Coordinating Center, Bern, Switzerland.

Simona Berardi Vilei (SB)

SAKK Coordinating Center, Bern, Switzerland.

Michele Ghielmini (M)

Division of Medical Oncology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.

Eva Kimby (E)

Unit of Hematology, Department of Medicine at Huddinge, Karolinska Institutet, Stockholm, Sweden.

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Classifications MeSH