National, regional, and worldwide estimates of low birthweight in 2015, with trends from 2000: a systematic analysis.
Journal
The Lancet. Global health
ISSN: 2214-109X
Titre abrégé: Lancet Glob Health
Pays: England
ID NLM: 101613665
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
12
10
2018
accepted:
19
11
2018
pubmed:
20
5
2019
medline:
27
5
2020
entrez:
20
5
2019
Statut:
ppublish
Résumé
Low birthweight (LBW) of less than 2500 g is an important marker of maternal and fetal health, predicting mortality, stunting, and adult-onset chronic conditions. Global nutrition targets set at the World Health Assembly in 2012 include an ambitious 30% reduction in LBW prevalence between 2012 and 2025. Estimates to track progress towards this target are lacking; with this analysis, we aim to assist in setting a baseline against which to assess progress towards the achievement of the World Health Assembly targets. We sought to identify all available LBW input data for livebirths for the years 2000-16. We considered population-based national or nationally representative datasets for inclusion if they contained information on birthweight or LBW prevalence for livebirths. A new method for survey adjustment was developed and used. For 57 countries with higher quality time-series data, we smoothed country-reported trends in birthweight data by use of B-spline regression. For all other countries, we estimated LBW prevalence and trends by use of a restricted maximum likelihood approach with country-level random effects. Uncertainty ranges were obtained through bootstrapping. Results were summed at the regional and worldwide level. We collated 1447 country-years of birthweight data (281 million births) for 148 countries of 195 UN member states (47 countries had no data meeting inclusion criteria). The estimated worldwide LBW prevalence in 2015 was 14·6% (uncertainty range [UR] 12·4-17·1) compared with 17·5% (14·1-21·3) in 2000 (average annual reduction rate [AARR] 1·23%). In 2015, an estimated 20·5 million (UR 17·4-24·0 million) livebirths were LBW, 91% from low-and-middle income countries, mainly southern Asia (48%) and sub-Saharan Africa (24%). Although these estimates suggest some progress in reducing LBW between 2000 and 2015, achieving the 2·74% AARR required between 2012 and 2025 to meet the global nutrition target will require more than doubling progress, involving both improved measurement and programme investments to address the causes of LBW throughout the lifecycle. Bill & Melinda Gates Foundation, The Children's Investment Fund Foundation, United Nations Children's Fund (UNICEF), and WHO.
Sections du résumé
BACKGROUND
Low birthweight (LBW) of less than 2500 g is an important marker of maternal and fetal health, predicting mortality, stunting, and adult-onset chronic conditions. Global nutrition targets set at the World Health Assembly in 2012 include an ambitious 30% reduction in LBW prevalence between 2012 and 2025. Estimates to track progress towards this target are lacking; with this analysis, we aim to assist in setting a baseline against which to assess progress towards the achievement of the World Health Assembly targets.
METHODS
We sought to identify all available LBW input data for livebirths for the years 2000-16. We considered population-based national or nationally representative datasets for inclusion if they contained information on birthweight or LBW prevalence for livebirths. A new method for survey adjustment was developed and used. For 57 countries with higher quality time-series data, we smoothed country-reported trends in birthweight data by use of B-spline regression. For all other countries, we estimated LBW prevalence and trends by use of a restricted maximum likelihood approach with country-level random effects. Uncertainty ranges were obtained through bootstrapping. Results were summed at the regional and worldwide level.
FINDINGS
We collated 1447 country-years of birthweight data (281 million births) for 148 countries of 195 UN member states (47 countries had no data meeting inclusion criteria). The estimated worldwide LBW prevalence in 2015 was 14·6% (uncertainty range [UR] 12·4-17·1) compared with 17·5% (14·1-21·3) in 2000 (average annual reduction rate [AARR] 1·23%). In 2015, an estimated 20·5 million (UR 17·4-24·0 million) livebirths were LBW, 91% from low-and-middle income countries, mainly southern Asia (48%) and sub-Saharan Africa (24%).
INTERPRETATION
Although these estimates suggest some progress in reducing LBW between 2000 and 2015, achieving the 2·74% AARR required between 2012 and 2025 to meet the global nutrition target will require more than doubling progress, involving both improved measurement and programme investments to address the causes of LBW throughout the lifecycle.
FUNDING
Bill & Melinda Gates Foundation, The Children's Investment Fund Foundation, United Nations Children's Fund (UNICEF), and WHO.
Identifiants
pubmed: 31103470
pii: S2214-109X(18)30565-5
doi: 10.1016/S2214-109X(18)30565-5
pmc: PMC6560046
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e849-e860Subventions
Organisme : World Health Organization
ID : 001
Pays : International
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2019 UNICEF and World Health Organization. Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved.
Références
J Perinatol. 2005 Jan;25(1):11-3
pubmed: 15496868
Lancet. 2005 Mar 5-11;365(9462):891-900
pubmed: 15752534
Bull World Health Organ. 2005 Mar;83(3):178-85
pubmed: 15798841
Am J Hum Biol. 2007 Jan-Feb;19(1):1-19
pubmed: 17160980
Matern Child Health J. 2011 Jan;15(1):12-8
pubmed: 20063179
PLoS Med. 2010 Nov 30;7(11):e1001006
pubmed: 21152416
Lancet. 2012 Jun 9;379(9832):2162-72
pubmed: 22682464
Lancet. 2013 Aug 3;382(9890):417-425
pubmed: 23746775
Am J Obstet Gynecol. 2013 Nov;209(5):428.e1-6
pubmed: 23816839
Nestle Nutr Inst Workshop Ser. 2013;74:11-25
pubmed: 23887100
Cien Saude Colet. 2013 Aug;18(8):2443-52
pubmed: 23896927
Int J Epidemiol. 2013 Oct;42(5):1340-55
pubmed: 23920141
Pediatr Res. 2013 Dec;74 Suppl 1:17-34
pubmed: 24366461
Lancet. 2014 Jul 12;384(9938):189-205
pubmed: 24853593
Lancet Glob Health. 2013 Jul;1(1):e26-36
pubmed: 25103583
Lancet. 2014 Sep 6;384(9946):857-68
pubmed: 25209487
CMAJ. 2015 Jan 6;187(1):E32-E40
pubmed: 25384653
PLoS One. 2014 Dec 02;9(12):e113920
pubmed: 25463771
Adv Nutr. 2015 Jan 15;6(1):134-5
pubmed: 25593153
Reprod Health. 2015;12 Suppl 2:S8
pubmed: 26063350
BMC Pregnancy Childbirth. 2015;15 Suppl 2:S8
pubmed: 26391444
Am J Obstet Gynecol. 2015 Oct;213(4):449.e1-449.e41
pubmed: 26410205
Am J Obstet Gynecol. 2016 Apr;214(4):509.e1-509.e7
pubmed: 26546850
Lancet Glob Health. 2016 Feb;4(2):e98-e108
pubmed: 26795602
Matern Child Health J. 2017 Feb;21(2):283-289
pubmed: 27449779
PLoS One. 2016 Dec 28;11(12):e0168743
pubmed: 28030594
Nicotine Tob Res. 2017 May 1;19(5):497-505
pubmed: 28403455
PLoS One. 2017 Oct 17;12(10):e0186287
pubmed: 29040334
Pediatrics. 2017 Dec;140(6):null
pubmed: 29150458
Paediatr Perinat Epidemiol. 2018 Mar;32(2):184-196
pubmed: 29253317
J Glob Health. 2018 Jun;8(1):010604
pubmed: 29899981
Nihon Eiseigaku Zasshi. 1993 Feb;47(6):1050-7
pubmed: 8492482