Parkinson's disease and long-term exposure to outdoor air pollution: A matched case-control study in the Netherlands.


Journal

Environment international
ISSN: 1873-6750
Titre abrégé: Environ Int
Pays: Netherlands
ID NLM: 7807270

Informations de publication

Date de publication:
08 2019
Historique:
received: 09 01 2019
revised: 26 04 2019
accepted: 28 04 2019
pubmed: 20 5 2019
medline: 8 11 2019
entrez: 20 5 2019
Statut: ppublish

Résumé

There is some evidence to suggest an association between ambient air pollution and development of Parkinson's disease (PD). However, the small number of studies published to date has reported inconsistent findings. To assess the association between long-term exposure to ambient air pollution constituents and the development of PD. Air pollution exposures (particulate matter with aerodynamic diameter <10 μm [PM Overall, no significant, positive relationship between ambient air pollutants and PD was observed. The odds ratio (OR) for PD associated with an increase from the first quartile of NO We found no clear association between 16 years of residential exposure to ambient air pollution and the development of PD in The Netherlands.

Sections du résumé

BACKGROUND
There is some evidence to suggest an association between ambient air pollution and development of Parkinson's disease (PD). However, the small number of studies published to date has reported inconsistent findings.
OBJECTIVES
To assess the association between long-term exposure to ambient air pollution constituents and the development of PD.
METHODS
Air pollution exposures (particulate matter with aerodynamic diameter <10 μm [PM
RESULTS
Overall, no significant, positive relationship between ambient air pollutants and PD was observed. The odds ratio (OR) for PD associated with an increase from the first quartile of NO
CONCLUSIONS
We found no clear association between 16 years of residential exposure to ambient air pollution and the development of PD in The Netherlands.

Identifiants

pubmed: 31103844
pii: S0160-4120(19)30098-4
doi: 10.1016/j.envint.2019.04.069
pii:
doi:

Substances chimiques

Air Pollutants 0
Nitrogen Oxides 0
Particulate Matter 0
Soot 0

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

28-34

Informations de copyright

Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

Rosario Toro (R)

Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile.

George S Downward (GS)

Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands. Electronic address: g.s.downward@uu.nl.

Marianne van der Mark (M)

Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands.

Maartje Brouwer (M)

Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands.

Anke Huss (A)

Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands.

Susan Peters (S)

Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands; Department of Neurology, University Medical Centre Utrecht, Utrecht, the Netherlands.

Gerard Hoek (G)

Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands.

Peter Nijssen (P)

Department of Neurology, Elisabeth-TweeSteden Hospital, Tilburg, the Netherlands.

Wim M Mulleners (WM)

Department of Neurology, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands.

Antonetta Sas (A)

Department of Neurology, Vlietland Hospital, Schiedam, the Netherlands.

Teus van Laar (T)

Department of Neurology, University Medical Centre Groningen, Groningen, the Netherlands.

Hans Kromhout (H)

Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands.

Roel Vermeulen (R)

Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, the Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.

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Classifications MeSH