EDTA antimicrobial canine otitis externa combination robenidine

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2019
Historique:
received: 23 10 2018
accepted: 01 04 2019
entrez: 21 5 2019
pubmed: 21 5 2019
medline: 21 5 2019
Statut: epublish

Résumé

The emergence and global spread of antimicrobial resistance among bacterial pathogens demand alternative strategies to treat life-threatening infections. Combination drugs and repurposing of old compounds with known safety profiles that are not currently used in human medicine can address the problem of multidrug-resistant infections and promote antimicrobial stewardship in veterinary medicine. In this study, the antimicrobial activity of robenidine alone or in combination with ethylenediaminetetraacetic acid (EDTA) or polymyxin B nonapeptide (PMBN) against Gram-negative bacterial pathogens, including those associated with canine otitis externa and human skin and soft tissue infection, was evaluated

Identifiants

pubmed: 31105656
doi: 10.3389/fmicb.2019.00837
pmc: PMC6494957
doi:

Types de publication

Journal Article

Langues

eng

Pagination

837

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Auteurs

Manouchehr Khazandi (M)

Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, SA, Australia.

Hongfei Pi (H)

Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, SA, Australia.

Wei Yee Chan (WY)

Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, SA, Australia.

Abiodun David Ogunniyi (AD)

Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, SA, Australia.

Jowenna Xiao Feng Sim (JXF)

School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA, Australia.

Henrietta Venter (H)

School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA, Australia.

Sanjay Garg (S)

School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA, Australia.

Stephen W Page (SW)

Neoculi Pty Ltd., Burwood, VIC, Australia.

Peter B Hill (PB)

Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, SA, Australia.

Adam McCluskey (A)

Chemistry, School of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW, Australia.

Darren J Trott (DJ)

Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, SA, Australia.

Classifications MeSH