Advances in cerebral amyloid angiopathy imaging.
cerebral amyloid angiopathy
cerebral microbleed
magnetic resonance imaging
positron emitting tomography
small vessel disease
Journal
Therapeutic advances in neurological disorders
ISSN: 1756-2856
Titre abrégé: Ther Adv Neurol Disord
Pays: England
ID NLM: 101480242
Informations de publication
Date de publication:
2019
2019
Historique:
received:
29
11
2018
accepted:
25
03
2019
entrez:
21
5
2019
pubmed:
21
5
2019
medline:
21
5
2019
Statut:
epublish
Résumé
Cerebral amyloid angiopathy (CAA) is a cerebral small vessel disease caused by β -amyloid (Aβ) deposition at the leptomeningeal vessel walls. It is a common cause of spontaneous intracerebral hemorrhage and a frequent comorbidity in Alzheimer's disease. The high recurrent hemorrhage rate in CAA makes it very important to recognize this disease to avoid potential harmful medication. Imaging studies play an important role in diagnosis and research of CAA. Conventional computed tomography and magnetic resonance imaging (MRI) methods reveal anatomical alterations, and remains as the most reliable tool in identifying CAA according to modified Boston criteria. The vascular injuries of CAA result in both hemorrhagic and ischemic manifestations and related structural changes on MRI, including cerebral microbleeds, cortical superficial siderosis, white matter hyperintensity, MRI-visible perivascular spaces, and cortical microinfarcts. As imaging techniques advance, not only does the resolution of conventional imaging improve, but novel skills in functional and molecular imaging studies also enable
Identifiants
pubmed: 31105769
doi: 10.1177/1756286419844113
pii: 10.1177_1756286419844113
pmc: PMC6501479
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1756286419844113Déclaration de conflit d'intérêts
Conflict of interest statement: The authors declare that there is no conflict of interest.
Références
Neurology. 2001 Feb 27;56(4):537-9
pubmed: 11222803
Ann Neurol. 2001 Dec;50(6):765-72
pubmed: 11761474
Brain. 2004 Oct;127(Pt 10):2265-75
pubmed: 15282216
Neurology. 2004 Nov 9;63(9):1606-12
pubmed: 15534243
Neurology. 2007 Apr 24;68(17):1411-6
pubmed: 17452586
Radiographics. 2007 Jul-Aug;27(4):1071-86
pubmed: 17620468
J Neurol. 2008 Jan;255(1):70-6
pubmed: 18202817
Neurology. 2009 Jan 13;72(2):171-6
pubmed: 19139370
J Neurol. 2008 Nov;255(11):1679-86
pubmed: 19156486
Lancet Neurol. 2009 Feb;8(2):165-74
pubmed: 19161908
Stroke. 2009 Apr;40(4):1269-74
pubmed: 19228848
Stroke. 2009 Nov;40(11):3455-60
pubmed: 19762705
Stroke. 2010 Jan;41(1):34-40
pubmed: 19926840
Stroke. 2010 Mar;41(3):450-4
pubmed: 20056930
Neurology. 2010 Feb 9;74(6):487-93
pubmed: 20142615
Neurology. 2010 Apr 27;74(17):1346-50
pubmed: 20421578
Ann Neurol. 2010 Oct;68(4):545-8
pubmed: 20865701
Neurology. 2010 Dec 14;75(24):2221-8
pubmed: 21172845
Ann Neurol. 2011 Feb;69(2):320-7
pubmed: 21387377
J Neurol. 2012 Mar;259(3):530-6
pubmed: 21877206
Neurology. 2012 Jan 31;78(5):326-33
pubmed: 22262748
Lancet Neurol. 2012 Mar;11(3):241-9
pubmed: 22305802
Neurology. 2012 Jul 24;79(4):320-6
pubmed: 22786597
Stroke. 2012 Sep;43(9):2324-30
pubmed: 22798323
Ann Neurol. 2012 Jul;72(1):76-81
pubmed: 22829269
Stroke. 2012 Oct;43(10):2592-7
pubmed: 22858729
Int J Stroke. 2013 Feb;8(2):105-8
pubmed: 23336261
Ann Neurol. 2013 Apr;73(4):529-36
pubmed: 23424091
Lancet Neurol. 2013 Aug;12(8):822-38
pubmed: 23867200
Neurology. 2013 Nov 5;81(19):1659-65
pubmed: 24097810
Lancet Neurol. 2014 Apr;13(4):419-28
pubmed: 24581702
Alzheimers Res Ther. 2014 Jun 11;6(3):33
pubmed: 24987468
Stroke. 2014 Sep;45(9):2636-42
pubmed: 25052320
Neurology. 2014 Aug 26;83(9):794-800
pubmed: 25063759
Brain. 2015 Jan;138(Pt 1):179-88
pubmed: 25367025
J Neuroimaging. 2015 May-Jun;25(3):420-9
pubmed: 25523388
Neurology. 2015 Feb 24;84(8):849-55
pubmed: 25632096
J Stroke. 2015 Jan;17(1):17-30
pubmed: 25692104
Alzheimers Dement. 2015 Dec;11(12):1480-1488
pubmed: 26079413
Brain. 2015 Aug;138(Pt 8):2126-39
pubmed: 26115675
PLoS One. 2015 Oct 06;10(10):e0139926
pubmed: 26439113
Neurology. 2016 Feb 9;86(6):505-11
pubmed: 26747886
JAMA Neurol. 2016 Jun 1;73(6):675-83
pubmed: 27088650
Neuroimage Clin. 2016 Mar 03;11:461-467
pubmed: 27104140
Lancet Neurol. 2016 Jul;15(8):811-819
pubmed: 27180034
Curr Neurovasc Res. 2016;13(3):244-8
pubmed: 27229323
Stroke. 2016 Oct;47(10):2470-5
pubmed: 27576378
Brain. 2016 Dec;139(Pt 12):3151-3162
pubmed: 27645801
Acta Neuropathol. 2017 Mar;133(3):409-415
pubmed: 27771772
Ann Neurol. 2017 Mar;81(3):333-343
pubmed: 28019651
Neurology. 2017 Mar 21;88(12):1157-1164
pubmed: 28228568
J Alzheimers Dis. 2017;57(3):711-716
pubmed: 28282808
Brain. 2017 Jul 1;140(7):1829-1850
pubmed: 28334869
Stroke. 2017 May;48(5):1404-1407
pubmed: 28364025
Neurology. 2017 Jun 6;88(23):2162-2168
pubmed: 28476760
Neuroimage Clin. 2017 May 05;15:247-263
pubmed: 28560150
PLoS One. 2017 Jul 10;12(7):e0180923
pubmed: 28700676
Neurology. 2017 Oct 3;89(14):1490-1498
pubmed: 28855406
J Neurol Neurosurg Psychiatry. 2018 Apr;89(4):410-417
pubmed: 29070646
Neurology. 2017 Nov 21;89(21):2128-2135
pubmed: 29070669
Neurology. 2018 Jan 9;90(2):e119-e126
pubmed: 29247070
Lancet Neurol. 2018 Mar;17(3):232-240
pubmed: 29331631
Neurocrit Care. 2018 Aug;29(1):77-83
pubmed: 29556933
Stroke. 2018 Jun;49(6):1515-1517
pubmed: 29695464
Stroke. 2018 Aug;49(8):1899-1905
pubmed: 29986931
Neurology. 2019 Feb 19;92(8):e774-e781
pubmed: 30674594
J Neurol. 1987 Aug;234(6):371-6
pubmed: 3655840