Depression and Incidence of Frailty in Older People From Six Latin American Countries.
Depression
epidemiology
frailty
low- and middle-income countries
older age
Journal
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
ISSN: 1545-7214
Titre abrégé: Am J Geriatr Psychiatry
Pays: England
ID NLM: 9309609
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
received:
21
02
2019
revised:
20
04
2019
accepted:
22
04
2019
pubmed:
22
5
2019
medline:
4
9
2020
entrez:
22
5
2019
Statut:
ppublish
Résumé
Frailty and depression are highly comorbid conditions, but the casual direction is unclear and has not been explored in low- and middle-income countries. The aim of this study was to investigate the potential impact of depression on incident frailty in older people living in Latin America. This study was based on a population-based cohort of 12,844 people aged 65 or older from six Latin American countries (Cuba, Dominican Republic, Mexico, Venezuela, Puerto Rico, and Peru), part of the 10/66 cohort study. Two types of frailty measures were used: a modified Fried frailty phenotype and a multidimensional frailty criterion, which included measures from cognition, sensory, nutrition, and physical dimensions. Depression was assessed using EURO-D and International Classification of Diseases, Tenth Revision criteria. A competing risk model was used to examine the associations between baseline depression and incidence of frailty in the 3-5 years of follow-up, accounting for sociodemographic and health factors and the competing event of frailty-free death. Depression was associated with a 59% increased hazard of developing frailty using the modified Fried phenotype (subdistribution hazard ratio [SHR]: 1.59; 95% confidence interval [CI]: 1.40, 1.80) and 19% for multidimensional frailty (SHR: 1.19; 95% CI: 1.06, 1.33) after adjusting for sociodemographic factors, physical impairments, and dementia. The associations between depression and the multidimensional frailty criteria were homogenous across all the sites (Higgins I Depression may play a key role in the development of frailty. Pathways addressing the association between physical and mental health in older people need to be further investigated in future research.
Identifiants
pubmed: 31109899
pii: S1064-7481(19)30342-2
doi: 10.1016/j.jagp.2019.04.008
pmc: PMC6742503
mid: EMS83867
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1072-1079Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Department of Health
ID : ICA-CL-2017-03-001
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/K021907/1
Pays : United Kingdom
Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.
Références
Arch Intern Med. 2000 Jul 24;160(14):2101-7
pubmed: 10904452
J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):M146-56
pubmed: 11253156
Lancet. 2003 Mar 15;361(9361):909-17
pubmed: 12648969
BMJ. 2003 Sep 6;327(7414):557-60
pubmed: 12958120
Age Ageing. 2003 Nov;32(6):650-6
pubmed: 14600007
Am J Med. 2005 Nov;118(11):1225-31
pubmed: 16271906
J Gerontol A Biol Sci Med Sci. 2007 Jul;62(7):722-7
pubmed: 17634318
BMC Public Health. 2007 Jul 20;7:165
pubmed: 17659078
J Gerontol A Biol Sci Med Sci. 2008 Dec;63(12):1399-406
pubmed: 19126855
BMC Geriatr. 2010 Aug 24;10:57
pubmed: 20731877
Ageing Res Rev. 2011 Jan;10(1):104-14
pubmed: 20850567
BMJ. 2011 Sep 28;343:d5219
pubmed: 21957206
Br J Psychiatry. 2011 Dec;199(6):485-91
pubmed: 22016438
J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):62-7
pubmed: 22511289
J Am Geriatr Soc. 2012 Aug;60(8):1487-92
pubmed: 22881367
Am J Public Health. 2013 May;103(5):777-80
pubmed: 23488489
Am J Geriatr Psychiatry. 2013 Jun;21(6):560-9
pubmed: 23567406
Eur Heart J. 2014 Jun 1;35(21):1365-72
pubmed: 24282187
Aging Ment Health. 2015;19(9):762-72
pubmed: 25319638
BMC Psychiatry. 2015 Feb 05;15:12
pubmed: 25652111
BMC Med. 2015 Jun 10;13:138
pubmed: 26063168
J Affect Disord. 2015 Sep 15;184:129-36
pubmed: 26092097
BMJ Open. 2015 Sep 02;5(9):e008462
pubmed: 26338685
J Affect Disord. 2016 Jan 15;190:362-368
pubmed: 26544620
Nat Rev Immunol. 2016 Jan;16(1):22-34
pubmed: 26711676
Clin Interv Aging. 2015 Dec 15;10:1947-58
pubmed: 26719681
Int J Epidemiol. 2017 Apr 1;46(2):406-406i
pubmed: 27154633
Ageing Res Rev. 2016 Nov;31:1-8
pubmed: 27592340
Am J Geriatr Psychiatry. 2016 Nov;24(11):1084-1094
pubmed: 27618646
PLoS One. 2017 Feb 2;12(2):e0170878
pubmed: 28152084
Ageing Res Rev. 2017 Jul;36:78-87
pubmed: 28366616
Age Ageing. 2018 Mar 1;47(2):193-200
pubmed: 29040347
Exp Gerontol. 2018 Feb;102:109-132
pubmed: 29237576
J Am Med Dir Assoc. 2018 Apr;19(4):287-295.e4
pubmed: 29306607
Am J Psychiatry. 2018 Jul 1;175(7):631-648
pubmed: 29690792
J Gerontol B Psychol Sci Soc Sci. 1998 Jan;53(1):S9-16
pubmed: 9469175