Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE).
Cardiovascular rehabilitation
Cardiovascular risk
Ketone bodies
Obesity
Type 2 diabetes
Weight loss
Journal
Journal of endocrinological investigation
ISSN: 1720-8386
Titre abrégé: J Endocrinol Invest
Pays: Italy
ID NLM: 7806594
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
13
03
2019
accepted:
07
05
2019
pubmed:
22
5
2019
medline:
7
3
2020
entrez:
22
5
2019
Statut:
ppublish
Résumé
Weight loss is a milestone in the prevention of chronic diseases associated with high morbility and mortality in industrialized countries. Very-low calorie ketogenic diets (VLCKDs) are increasingly used in clinical practice for weight loss and management of obesity-related comorbidities. Despite evidence on the clinical benefits of VLCKDs is rapidly emerging, some concern still exists about their potential risks and their use in the long-term, due to paucity of clinical studies. Notably, there is an important lack of guidelines on this topic, and the use and implementation of VLCKDs occurs vastly in the absence of clear evidence-based indications. We describe here the biochemistry, benefits and risks of VLCKDs, and provide recommendations on the correct use of this therapeutic approach for weight loss and management of metabolic diseases at different stages of life.
Sections du résumé
BACKGROUND
BACKGROUND
Weight loss is a milestone in the prevention of chronic diseases associated with high morbility and mortality in industrialized countries. Very-low calorie ketogenic diets (VLCKDs) are increasingly used in clinical practice for weight loss and management of obesity-related comorbidities. Despite evidence on the clinical benefits of VLCKDs is rapidly emerging, some concern still exists about their potential risks and their use in the long-term, due to paucity of clinical studies. Notably, there is an important lack of guidelines on this topic, and the use and implementation of VLCKDs occurs vastly in the absence of clear evidence-based indications.
PURPOSE
OBJECTIVE
We describe here the biochemistry, benefits and risks of VLCKDs, and provide recommendations on the correct use of this therapeutic approach for weight loss and management of metabolic diseases at different stages of life.
Identifiants
pubmed: 31111407
doi: 10.1007/s40618-019-01061-2
pii: 10.1007/s40618-019-01061-2
doi:
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1365-1386Investigateurs
Massimiliano Caprio
(M)
Fausto Bogazzi
(F)
Guglielmo Beccuti
(G)
Bernadette Biondi
(B)
Salvatore Cannavò
(S)
Iacopo Chiodini
(I)
Giuseppe De Feudis
(G)
Simona Di Francesco
(S)
Aldo Di Gregorio
(A)
Francesco Fallo
(F)
Carlo Foresta
(C)
Gilberta Giacchetti
(G)
Riccarda Granata
(R)
Andrea M Isidori
(AM)
Paolo Magni
(P)
Pasquale Maiellaro
(P)
Mirko Parasiliti Caprino
(MP)
Rosario Pivonello
(R)
Riccardo Pofi
(R)
Alfredo Pontecorvi
(A)
Chiara Simeoli
(C)
Commentaires et corrections
Type : CommentIn
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