Latitudinal variation in MS incidence in Scotland.


Journal

Multiple sclerosis and related disorders
ISSN: 2211-0356
Titre abrégé: Mult Scler Relat Disord
Pays: Netherlands
ID NLM: 101580247

Informations de publication

Date de publication:
Jul 2019
Historique:
received: 10 01 2019
revised: 18 04 2019
accepted: 26 04 2019
pubmed: 22 5 2019
medline: 31 12 2019
entrez: 22 5 2019
Statut: ppublish

Résumé

To explore the effect of latitude on incidence of multiple sclerosis (MS) in Scotland. MS case data (2010-2015) was ascertained from the Scottish Multiple Sclerosis Register. Patient's postcode at diagnosis was linked to the Scottish Index of Multiple Deprivation (SIMD). Geographical data from SIMD was converted into latitude and longitude and patients were grouped by latitude band. A linear regression analysis was then performed. MS Cumulative Incidence was compared to population density calculated from SIMD. Latitude was associated with MS Incidence rate. Using a linear regression analysis (r We found an increasing incidence of MS with latitude without any relationship to population in Scotland. The reasons for this are likely to be multifactorial.

Identifiants

pubmed: 31112929
pii: S2211-0348(19)30192-0
doi: 10.1016/j.msard.2019.04.032
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

116-122

Informations de copyright

Copyright © 2019. Published by Elsevier B.V.

Auteurs

James Joseph McDonald (JJ)

Department of Neurology, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN, United Kingdom. Electronic address: jmcdonald10@nhs.net.

Belinda Weller (B)

Scottish MS Register, Edinburgh, United Kingdom.

Martin O'Neil (M)

Scottish MS Register, Edinburgh, United Kingdom.

Chrissie Waters (C)

Scottish MS Register, Edinburgh, United Kingdom.

Jonathan O'Riordan (J)

Department of Neurology, Ninewells Hospital and Medical School, Dundee, United Kingdom.
Scottish MS Register, Edinburgh, United Kingdom.

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Classifications MeSH