Vernal Keratoconjunctivitis: an update focused on clinical grading system.

Clinical markers Diagnosis Grading Vernal keratoconjunctivitis

Journal

Italian journal of pediatrics
ISSN: 1824-7288
Titre abrégé: Ital J Pediatr
Pays: England
ID NLM: 101510759

Informations de publication

Date de publication:
21 May 2019
Historique:
received: 01 11 2018
accepted: 05 05 2019
entrez: 23 5 2019
pubmed: 23 5 2019
medline: 4 1 2020
Statut: epublish

Résumé

Vernal keratoconjunctivitis (VKC) is a severe disease with a prevalence of < 1 case out of 10,000 in Europe, which occurs mainly in pediatric age and is characterized by a severe and often bilateral chronic inflammation of the ocular surface. The diagnosis is generally confirmed by the finding at the ocular examination of conjunctival hyperemia, papillary hypertrophy in the tarsal conjunctiva, giant papillae, papillae in the limbus region. Aim of this review is to provide an updated overview on the disease focused on clinical grading system, searching papers published in the last decade on VKC in scientific databases. Currently there are no standardized criteria for diagnosis of VKC and there is no uniformity to define disease severity, which makes difficult to diagnose and treat the disease. Given the wide overlap of the symptoms of VKC with the allergic conjunctivitis, criteria of probable, possible or improbable diagnosis are needed, providing pediatricians with parameters useful for deciding whether to drive the patient to the ophthalmologist for diagnostic confirmation.

Identifiants

pubmed: 31113464
doi: 10.1186/s13052-019-0656-4
pii: 10.1186/s13052-019-0656-4
pmc: PMC6528205
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

64

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Auteurs

A M Zicari (AM)

Department of Pediatrics, "Sapienza" University of Rome, Viale Regina Elena 324, Rome, Italy.

G Capata (G)

Department of Pediatrics, "Sapienza" University of Rome, Viale Regina Elena 324, Rome, Italy. giulia.capata@gmail.com.

M Nebbioso (M)

Department of Sense Organs, "Sapienza" University of Rome, Rome, Italy.

G De Castro (G)

Department of Pediatrics, "Sapienza" University of Rome, Viale Regina Elena 324, Rome, Italy.

F Midulla (F)

Department of Pediatrics, "Sapienza" University of Rome, Viale Regina Elena 324, Rome, Italy.

L Leonardi (L)

Department of Pediatrics, "Sapienza" University of Rome, Viale Regina Elena 324, Rome, Italy.

L Loffredo (L)

Department of Internal Medicine and Medical Specialities, "Sapienza" University of Rome, Rome, Italy.

A Spalice (A)

Department of Pediatrics, "Sapienza" University of Rome, Viale Regina Elena 324, Rome, Italy.

L Perri (L)

Department of Internal Medicine and Medical Specialities, "Sapienza" University of Rome, Rome, Italy.

M Duse (M)

Department of Pediatrics, "Sapienza" University of Rome, Viale Regina Elena 324, Rome, Italy.

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