Paediatrician's perspective of infant gut microbiome research: current status and challenges.


Journal

Archives of disease in childhood
ISSN: 1468-2044
Titre abrégé: Arch Dis Child
Pays: England
ID NLM: 0372434

Informations de publication

Date de publication:
07 2019
Historique:
received: 21 01 2019
revised: 26 03 2019
accepted: 27 03 2019
pubmed: 23 5 2019
medline: 25 2 2020
entrez: 23 5 2019
Statut: ppublish

Résumé

Due to its innately intriguing nature and recent genomic technological advances, gut microbiome research has been at the epicentre of medical research for over a decade now. Despite the degree of publicisation, a comprehensive understanding and, therefore, acceptance of the area as a whole may be somewhat lacking within the broader medical community. This paper summarises the main analytical techniques and tools currently applied to compositional microbiome research. In addition, we outline five major lessons learnt from a decade of infant microbiome research, along with the current research gaps. Finally, we aim to provide an introduction and general guidelines relating to infant gut microbiome research for the practising paediatrician.

Identifiants

pubmed: 31113768
pii: archdischild-2019-316891
doi: 10.1136/archdischild-2019-316891
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

701-705

Informations de copyright

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Paul MacDaragh Ryan (PM)

School of Medicine, University College Cork, Cork, Ireland.

Catherine Stanton (C)

Teagasc Food Research Centre, Moorepark, Fermoy, Co. Cork, Ireland.
APC Microbiome Ireland, University College Cork, Cork, Ireland.

R Paul Ross (RP)

APC Microbiome Ireland, University College Cork, Cork, Ireland.

Alan L Kelly (AL)

School of Food and Nutritional Sciences, University College Cork, Cork, Ireland.

Eugene Dempsey (E)

Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.
Department of Neonatology, Cork University Maternity Hospital, Cork, Ireland.

C Anthony Ryan (CA)

Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.
Department of Neonatology, Cork University Maternity Hospital, Cork, Ireland.

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