Anthropometric Risk Factors for Cancers of the Biliary Tract in the Biliary Tract Cancers Pooling Project.


Journal

Cancer research
ISSN: 1538-7445
Titre abrégé: Cancer Res
Pays: United States
ID NLM: 2984705R

Informations de publication

Date de publication:
01 08 2019
Historique:
received: 06 02 2019
revised: 16 04 2019
accepted: 15 05 2019
pubmed: 23 5 2019
medline: 16 4 2020
entrez: 23 5 2019
Statut: ppublish

Résumé

Biliary tract cancers are rare but highly fatal with poorly understood etiology. Identifying potentially modifiable risk factors for these cancers is essential for prevention. Here we estimated the relationship between adiposity and cancer across the biliary tract, including cancers of the gallbladder (GBC), intrahepatic bile ducts (IHBDC), extrahepatic bile ducts (EHBDC), and the ampulla of Vater (AVC). We pooled data from 27 prospective cohorts with over 2.7 million adults. Adiposity was measured using baseline body mass index (BMI), waist circumference, hip circumference, waist-to-hip, and waist-to-height ratios. HRs and 95% confidence intervals (95% CI) were estimated using Cox proportional hazards models adjusted for sex, education, race, smoking, and alcohol consumption with age as the time metric and the baseline hazard stratified by study. During 37,883,648 person-years of follow-up, 1,343 GBC cases, 1,194 EHBDC cases, 784 IHBDC cases, and 623 AVC cases occurred. For each 5 kg/m

Identifiants

pubmed: 31113819
pii: 0008-5472.CAN-19-0459
doi: 10.1158/0008-5472.CAN-19-0459
pmc: PMC6759233
mid: NIHMS1530132
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

3973-3982

Subventions

Organisme : NCI NIH HHS
ID : P30 CA016087
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600002C
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA043092
Pays : United States
Organisme : NIEHS NIH HHS
ID : P30 ES000260
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA039742
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600004C
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL026490
Pays : United States
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : R01 CA040360
Pays : United States
Organisme : NHLBI NIH HHS
ID : RC1 HL099355
Pays : United States
Organisme : Cancer Research UK
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : UM1 CA182876
Pays : United States
Organisme : NCI NIH HHS
ID : P01 CA087969
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA152939
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600018C
Pays : United States
Organisme : British Heart Foundation
Pays : United Kingdom
Organisme : NHLBI NIH HHS
ID : R01 HL043851
Pays : United States
Organisme : NCI NIH HHS
ID : K05 CA154337
Pays : United States
Organisme : NCI NIH HHS
ID : P01 CA055075
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA182934
Pays : United States
Organisme : Intramural NIH HHS
ID : Z01 ES049030
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL034595
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA144034
Pays : United States
Organisme : Department of Health
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : UM1 CA182934
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600003C
Pays : United States
Organisme : Medical Research Council
Pays : United Kingdom
Organisme : Intramural NIH HHS
ID : Z99 CA999999
Pays : United States
Organisme : NCI NIH HHS
ID : P01 CA033619
Pays : United States
Organisme : NCI NIH HHS
ID : UM1 CA186107
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA047988
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600001C
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA080205
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL080467
Pays : United States
Organisme : NCI NIH HHS
ID : UM1 CA167552
Pays : United States
Organisme : NCI NIH HHS
ID : HHSN261201500005C
Pays : United States
Organisme : Intramural NIH HHS
ID : Z01 ES044005
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA097193
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA164973
Pays : United States

Informations de copyright

©2019 American Association for Cancer Research.

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Auteurs

Sarah S Jackson (SS)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland. sarah.jackson@nih.gov.

Alison L Van Dyke (AL)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Bin Zhu (B)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Ruth M Pfeiffer (RM)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Jessica L Petrick (JL)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Hans-Olov Adami (HO)

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Department of Health Management and Health Economics, University of Oslo, Oslo, Norway.

Demetrius Albanes (D)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Gabriella Andreotti (G)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Laura E Beane Freeman (LE)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Amy Berrington de González (A)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Julie E Buring (JE)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Andrew T Chan (AT)

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Yu Chen (Y)

Department of Population Health and Perlmutter Cancer Center, New York University School of Medicine, New York, New York.

Gary E Fraser (GE)

School of Public Health, Loma Linda University, Loma Linda, California.

Neal D Freedman (ND)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Yu-Tang Gao (YT)

Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China.

Susan M Gapstur (SM)

Behavioral and Epidemiology Research Group, American Cancer Society, Inc., Atlanta, Georgia.

J Michael Gaziano (JM)

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Boston Veteran Affairs Healthcare System, Boston, Massachusetts.

Graham G Giles (GG)

Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Parkville, Victoria, Australia.

Eric J Grant (EJ)

Department of Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan.

Francine Grodstein (F)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Patricia Hartge (P)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Mazda Jenab (M)

Section of Nutrition and Metabolism, International Agency for Research on Cancer (IARC-WHO), Lyon, France.

Cari M Kitahara (CM)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Synnove F Knutsen (SF)

School of Public Health, Loma Linda University, Loma Linda, California.

Woon-Puay Koh (WP)

Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.
Saw Swee Hock School of Public Health, National University of Singapore, Singapore.

Susanna C Larsson (SC)

Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

I-Min Lee (IM)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Linda M Liao (LM)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Juhua Luo (J)

Department of Epidemiology and Biostatistics, School of Public Health, Indiana University Bloomington, Bloomington, Indiana.

Emma E McGee (EE)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Roger L Milne (RL)

Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Parkville, Victoria, Australia.

Kristine R Monroe (KR)

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.

Marian L Neuhouser (ML)

Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.

Katie M O'Brien (KM)

Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.

Ulrike Peters (U)

Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Department of Epidemiology, University of Washington, Seattle, Washington.

Jenny N Poynter (JN)

Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Mark P Purdue (MP)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Kim Robien (K)

Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University, Washington, District of Columbia.

Dale P Sandler (DP)

Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.

Norie Sawada (N)

Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.

Catherine Schairer (C)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Howard D Sesso (HD)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Tracey G Simon (TG)

Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Rashmi Sinha (R)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Rachael Z Stolzenberg-Solomon (RZ)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Shoichiro Tsugane (S)

Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.

Renwei Wang (R)

UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania.

Elisabete Weiderpass (E)

International Agency for Research on Cancer (IARC), Lyon, France.

Stephanie J Weinstein (SJ)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Emily White (E)

Department of Epidemiology, University of Washington, Seattle, Washington.

Alicja Wolk (A)

Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Jian-Min Yuan (JM)

UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania.
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

Anne Zeleniuch-Jacquotte (A)

Department of Population Health and Perlmutter Cancer Center, New York University School of Medicine, New York, New York.

Xuehong Zhang (X)

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Katherine A McGlynn (KA)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

Peter T Campbell (PT)

Behavioral and Epidemiology Research Group, American Cancer Society, Inc., Atlanta, Georgia.

Jill Koshiol (J)

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

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