Volumetric evaluation of lumbar epidural fat distribution in epidural lipomatosis and back pain in patients who are obese: introducing a novel technique (Fat Finder algorithm).
MRI
adipose tissue biology
algorithms
low back pain
Journal
BMJ open diabetes research & care
ISSN: 2052-4897
Titre abrégé: BMJ Open Diabetes Res Care
Pays: England
ID NLM: 101641391
Informations de publication
Date de publication:
2019
2019
Historique:
received:
21
08
2018
revised:
30
11
2018
accepted:
19
12
2018
entrez:
23
5
2019
pubmed:
23
5
2019
medline:
23
5
2019
Statut:
epublish
Résumé
Spinal epidural lipomatosis (EL) represents an excessive deposition of unencapsulated adipose tissue in the spinal canal that can result in chronic back pain in patients who are obese with and without diabetes. We aim to calculate the total volumetric epidural fat on lumbar spine MRI in a predominately obese population and correlate total epidural fat to lower back pain (LBP) and body mass index (BMI). We developed a program (Fat Finder) to quantify volumetric distribution of epidural fat throughout the lumbar spine. Eleven patients with LBP were imaged using two MRI protocols: parallel axial slices and conventional clinical protocol. The distribution of epidural fat per level was analyzed and normalized to the spinal canal size. Our sample had an average age of 59.9 years and BMI of 31.57 kg/m The Fat Finder is a novel volumetric method to quantify epidural lumbar spinal fat. The epidural fat favors the lower spinal segment with direct proportionality between the fat volume and LBP score, independent of BMI.
Identifiants
pubmed: 31114695
doi: 10.1136/bmjdrc-2018-000599
pii: bmjdrc-2018-000599
pmc: PMC6501852
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e000599Déclaration de conflit d'intérêts
Competing interests: None declared.
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