NMR-Based Metabolomic Approach Tracks Potential Serum Biomarkers of Disease Progression in Patients with Type 2 Diabetes Mellitus.

NMR spectroscopy branched-chain amino acids metabolomics type 2 diabetes mellitus

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
21 May 2019
Historique:
received: 26 04 2019
revised: 10 05 2019
accepted: 15 05 2019
entrez: 24 5 2019
pubmed: 24 5 2019
medline: 24 5 2019
Statut: epublish

Résumé

Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by chronic hyperglycemia associated with alterations in carbohydrate, lipid, and protein metabolism. The prognosis of T2DM patients is highly dependent on the development of complications, and therefore the identification of biomarkers of T2DM progression, with minimally invasive techniques, is a huge need. In the present study, we applied a

Identifiants

DOI: 10.3390/jcm8050720 PMID: 31117294 PMC: PMC6571571
pubmed: 31117294
pii: jcm8050720
doi: 10.3390/jcm8050720
pmc: PMC6571571
pii:
doi:

Types de publication

Journal Article

Langues

eng

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

Am J Physiol Endocrinol Metab. 2001 Jan;280(1):E23-30
pubmed: 11120655
Diabetes. 2001 Aug;50(8):1807-12
pubmed: 11473042
Diabetes. 2002 Aug;51(8):2348-54
pubmed: 12145144
J Clin Invest. 1992 Oct;90(4):1323-7
pubmed: 1401068
Am J Med. 2004 Mar 8;116 Suppl 5A:2S-10S
pubmed: 15019858
Am Heart J. 2005 Jan;149(1):168-74
pubmed: 15660049
J Nutr. 2006 Jan;136(1 Suppl):319S-23S
pubmed: 16365106
BMC Genomics. 2006 Jun 08;7:142
pubmed: 16762068
J Nutr. 2007 Jun;137(6 Suppl 1):1539S-1547S; discussion 1548S
pubmed: 17513421
J Nutr. 2007 Jun;137(6 Suppl 1):1586S-1590S; discussion 1597S-1598S
pubmed: 17513431
Nat Protoc. 2007;2(11):2692-703
pubmed: 18007604
Diabetes Care. 2009 Sep;32(9):1678-83
pubmed: 19502541
Prog Lipid Res. 2010 Jan;49(1):61-75
pubmed: 19720082
Bioinformatics. 2010 Sep 15;26(18):2342-4
pubmed: 20628077
Diabetes Care. 2011 Jan;34(1):77-83
pubmed: 20937686
J Neurochem. 2011 Apr;117(2):309-20
pubmed: 21288239
Nat Med. 2011 Apr;17(4):448-53
pubmed: 21423183
Diabet Med. 2011 Nov;28(11):1388-94
pubmed: 21692845
Adv Nutr. 2011 Nov;2(6):445-56
pubmed: 22332087
Ageing Res Rev. 2013 Mar;12(2):685-98
pubmed: 22353383
Diabetes Care. 2012 Aug;35(8):1749-56
pubmed: 22563043
J Endocrinol. 2012 Oct;215(1):29-42
pubmed: 22718433
Diabetes Care. 2012 Oct;35(10):1961-7
pubmed: 22996180
Diabetes Care. 2013 Mar;36(3):648-55
pubmed: 23129134
J Clin Endocrinol Metab. 2013 Jun;98(6):E1060-5
pubmed: 23633210
Int J Comput Assist Radiol Surg. 2014 Jan;9(1):79-89
pubmed: 23797823
Hum Mol Genet. 2014 Sep 15;23(R1):R1-8
pubmed: 24651065
Mediators Inflamm. 2014;2014:973139
pubmed: 24803744
Cell Metab. 2014 Nov 4;20(5):898-909
pubmed: 25307860
Aging (Albany NY). 2014 Sep;6(9):771-87
pubmed: 25324472
Obes Res Clin Pract. 2015 Jul-Aug;9(4):336-45
pubmed: 25465494
PLoS One. 2015 Mar 20;10(3):e0119983
pubmed: 25793407
Hepat Med. 2015 Jun 03;7:29-35
pubmed: 26082668
IUBMB Life. 2015 Jul;67(7):506-13
pubmed: 26177573
Oncotarget. 2015 Nov 3;6(34):35372-82
pubmed: 26498351
J Clin Invest. 2016 Jan;126(1):12-22
pubmed: 26727229
Acta Med Iran. 2016 Jan;54(1):24-31
pubmed: 26853287
J Diabetes Res. 2016;2016:2108909
pubmed: 26881241
Eur Heart J. 2016 Aug 1;37(29):2315-2381
pubmed: 27222591
Curr Diab Rep. 2016 Aug;16(8):74
pubmed: 27319324
Oncotarget. 2016 Aug 9;7(32):50835-50844
pubmed: 27437767
Sci Rep. 2016 Jul 29;6:30785
pubmed: 27470195
Int J Epidemiol. 2016 Oct;45(5):1507-1516
pubmed: 27694567
PeerJ. 2016 Dec 15;4:e2740
pubmed: 27994965
J Am Coll Cardiol. 2016 Dec 27;68(25):2850-2870
pubmed: 28007146
Lancet. 2017 Jun 3;389(10085):2239-2251
pubmed: 28190580
BMC Med. 2017 Jul 19;15(1):131
pubmed: 28720102
J Diabetes Investig. 2018 Mar;9(2):244-255
pubmed: 28779528
Lancet Diabetes Endocrinol. 2017 Oct;5(10):788-798
pubmed: 28803840
Prog Cardiovasc Dis. 2017 Nov - Dec;60(3):422-434
pubmed: 28958751
Food Res Int. 2016 Dec;90:281-287
pubmed: 29195883
Clin Chim Acta. 2018 Feb;477:39-47
pubmed: 29197503
Oncotarget. 2017 Oct 16;8(55):93338-93348
pubmed: 29212153
Crit Rev Clin Lab Sci. 2018 Jan;55(1):21-32
pubmed: 29239245
Aging (Albany NY). 2018 Feb 4;10(2):178-196
pubmed: 29410390
J Proteome Res. 2018 Apr 6;17(4):1575-1585
pubmed: 29460634
Diabet Med. 2018 Jul;35(7):944-953
pubmed: 29633349
Diabetologia. 2018 Jul;61(7):1581-1591
pubmed: 29728717
Nucleic Acids Res. 2018 Jul 2;46(W1):W486-W494
pubmed: 29762782
Molecules. 2018 Sep 09;23(9):null
pubmed: 30205612
Mar Drugs. 2018 Oct 18;16(10):null
pubmed: 30340347
Diabetes Care. 2019 Jan;42(Suppl 1):S90-S102
pubmed: 30559235
Rev Med Microbiol. 2019 Jan;30(1):1-17
pubmed: 30662163
Appl Biochem Biotechnol. 2019 Jul;188(3):854-867
pubmed: 30706418
Am J Clin Nutr. 2019 Mar 1;109(3):626-634
pubmed: 30796776
Arch Biochem Biophys. 1969 Jan;129(1):75-8
pubmed: 4387558
Anal Chem. 1995 Mar 1;67(5):793-811
pubmed: 7762816

Auteurs

Laura Del Coco (L)

Department of Biological and Environmental Sciences and Technologies, University of Salento, via Monteroni, 73100 Lecce, Italy. laura.delcoco@unisalento.it.

Daniele Vergara (D)

Department of Biological and Environmental Sciences and Technologies, University of Salento, via Monteroni, 73100 Lecce, Italy. daniele.vergara@unisalento.it.

Serena De Matteis (S)

Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy. serena.dematteis@irst.emr.it.

Emanuela Mensà (E)

Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, Ancona, Italy. emanuela.mensa@gmail.com.

Jacopo Sabbatinelli (J)

Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, Ancona, Italy. jacopo.sabbatinelli@gmail.com.

Francesco Prattichizzo (F)

IRCCS MultiMedica, 20099 Milan, Italy. francesco.prattichizzo@multimedica.it.

Anna Rita Bonfigli (AR)

Scientific Direction, IRCCS INRCA, 60121 Ancona, Italy. a.bonfigli@inrca.it.

Gianluca Storci (G)

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, 40126 Bologna, Italy. gianluca.storci@unibo.it.

Sara Bravaccini (S)

Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy. sara.bravaccini@irst.emr.it.

Francesca Pirini (F)

Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy. francesca.pirini@irst.emr.it.

Andrea Ragusa (A)

Department of Biological and Environmental Sciences and Technologies, University of Salento, via Monteroni, 73100 Lecce, Italy. andrea.ragusa@unisalento.it.

Andrea Casadei-Gardini (A)

Division of Medical Oncology, Department of Medical and Surgical Sciences for Children and Adults, University Hospital of Modena, 41125 Modena, Italy. casadeigardini@gmail.com.

Massimiliano Bonafè (M)

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, 40126 Bologna, Italy. massimiliano.bonafe@unibo.it.

Michele Maffia (M)

Department of Biological and Environmental Sciences and Technologies, University of Salento, via Monteroni, 73100 Lecce, Italy. francesco.prattichizzo@multimedica.it.

Francesco Paolo Fanizzi (FP)

Department of Biological and Environmental Sciences and Technologies, University of Salento, via Monteroni, 73100 Lecce, Italy. fp.fanizzi@unisalento.it.

Fabiola Olivieri (F)

Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, Ancona, Italy. f.olivieri@univpm.it.
Center of Clinical Pathology and Innovative Therapy, IRCCS INRCA, 60121 Ancona, Italy. f.olivieri@univpm.it.

Anna Maria Giudetti (AM)

Department of Biological and Environmental Sciences and Technologies, University of Salento, via Monteroni, 73100 Lecce, Italy. anna.giudetti@unisalento.it.

Classifications MeSH