Reporting preclinical anesthesia study (REPEAT): Evaluating the quality of reporting in the preclinical anesthesiology literature.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2019
2019
Historique:
received:
09
10
2018
accepted:
29
03
2019
entrez:
24
5
2019
pubmed:
24
5
2019
medline:
14
1
2020
Statut:
epublish
Résumé
Poor reporting quality may contribute to irreproducibility of results and failed 'bench-to-bedside' translation. Consequently, guidelines have been developed to improve the complete and transparent reporting of in vivo preclinical studies. To examine the impact of such guidelines on core methodological and analytical reporting items in the preclinical anesthesiology literature, we sampled a cohort of studies. Preclinical in vivo studies published in Anesthesiology, Anesthesia & Analgesia, Anaesthesia, and the British Journal of Anaesthesia (2008-2009, 2014-2016) were identified. Data was extracted independently and in duplicate. Reporting completeness was assessed using the National Institutes of Health Principles and Guidelines for Reporting Preclinical Research. Risk ratios were used for comparative analyses. Of 7615 screened articles, 604 met our inclusion criteria and included experiments reporting on 52 490 animals. The most common topic of investigation was pain and analgesia (30%), rodents were most frequently used (77%), and studies were most commonly conducted in the United States (36%). Use of preclinical reporting guidelines was listed in 10% of applicable articles. A minority of studies fully reported on replicates (0.3%), randomization (10%), blinding (12%), sample-size estimation (3%), and inclusion/exclusion criteria (5%). Statistics were well reported (81%). Comparative analysis demonstrated few differences in reporting rigor between journals, including those that endorsed reporting guidelines. Principal items of study design were infrequently reported, with few differences between journals. Methods to improve implementation and adherence to community-based reporting guidelines may be necessary to increase transparent and consistent reporting in the preclinical anesthesiology literature.
Identifiants
pubmed: 31120888
doi: 10.1371/journal.pone.0215221
pii: PONE-D-18-29350
pmc: PMC6532843
doi:
Substances chimiques
Analgesics
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0215221Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Syst Rev. 2012 Nov 29;1:60
pubmed: 23194585
Nature. 2012 Mar 28;483(7391):531-3
pubmed: 22460880
Am J Med. 1982 Feb;72(2):233-40
pubmed: 7058834
JAMA. 2006 Oct 11;296(14):1731-2
pubmed: 17032985
BMJ. 2015 Jan 02;350:g7647
pubmed: 25555855
Nat Rev Drug Discov. 2004 Aug;3(8):711-5
pubmed: 15286737
Nature. 2012 Oct 11;490(7419):187-91
pubmed: 23060188
Circ Res. 2017 Jun 9;120(12):1916-1926
pubmed: 28373349
BMJ. 2004 Feb 28;328(7438):514-7
pubmed: 14988196
J Pain. 2018 Jun;19(6):571-588
pubmed: 29307749
Nature. 2014 Jan 30;505(7485):612-3
pubmed: 24482835
Anesthesiology. 2016 Nov;125(5):846-849
pubmed: 27575448
PLoS Comput Biol. 2013 Oct;9(10):e1003285
pubmed: 24204232
PLoS One. 2017 Sep 13;12(9):e0183591
pubmed: 28902887
Circulation. 1996 Nov 1;94(9):2324-36
pubmed: 8901707
Stroke. 2008 Oct;39(10):2824-9
pubmed: 18635842
PLoS Med. 2009 Jul 21;6(7):e1000100
pubmed: 19621070
Scientometrics. 2016;108:315-328
pubmed: 27390387
Syst Rev. 2012 Feb 10;1:10
pubmed: 22587960
Acad Emerg Med. 2003 Jun;10(6):684-7
pubmed: 12782533
J Cereb Blood Flow Metab. 2014 May;34(5):737-42
pubmed: 24549183
PLoS One. 2009 Nov 30;4(11):e7824
pubmed: 19956596
PLoS Biol. 2014 May 20;12(5):e1001863
pubmed: 24844265
JAMA. 2001 Aug 15;286(7):821-30
pubmed: 11497536
Am J Med. 2003 Apr 15;114(6):477-84
pubmed: 12731504
Trends Pharmacol Sci. 2016 Apr;37(4):290-302
pubmed: 26776451
PLoS Biol. 2010 Jun 29;8(6):e1000412
pubmed: 20613859
Anesthesiology. 2016 Apr;124(4):763-5
pubmed: 26845144
Trends Neurosci. 2007 Sep;30(9):433-9
pubmed: 17765332
J R Soc Med. 2008 Feb;101(2):95-8
pubmed: 18299631
Res Integr Peer Rev. 2019 Jun 12;4:12
pubmed: 31205756
Nature. 2015 Apr 16;520(7547):271-2
pubmed: 25877180
Stat Med. 1989 Apr;8(4):441-54
pubmed: 2727468
PLoS One. 2019 May 23;14(5):e0215221
pubmed: 31120888
Syst Rev. 2017 Jul 19;6(1):131
pubmed: 28720117
PLoS Biol. 2014 Jan;12(1):e1001756
pubmed: 24409096
PLoS Biol. 2015 Oct 13;13(10):e1002273
pubmed: 26460723
Stat Med. 1989 Apr;8(4):455-66
pubmed: 2727469
PLoS Biol. 2015 Jun 09;13(6):e1002165
pubmed: 26057340
Anesthesiology. 2011 Nov;115(5):909-11
pubmed: 21934485
J Cereb Blood Flow Metab. 2010 Sep;30(9):1619-24
pubmed: 20517323
Pain. 2016 Apr;157(4):901-909
pubmed: 26683237
PLoS One. 2016 Nov 17;11(11):e0166733
pubmed: 27855228