Global epidemiology of


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
22 05 2019
Historique:
entrez: 25 5 2019
pubmed: 28 5 2019
medline: 3 6 2020
Statut: epublish

Résumé

A key target of the WHO's 'Global Health Sector Strategy on sexually transmitted infections, 2016-2021' is achieving 90% reduction in All available studies of gonorrhoea infection in infertile populations, including infertility clinic attendees, will be systematically reviewed informed by Cochrane Collaboration guidelines. Findings will be reported following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Data sources will be searched using broad index terms exploded to cover all subheadings and free text terms with no language or year restriction. Any epidemiological measure in infertile populations based on primary data will be eligible for inclusion. Measures based on different assay types will be extracted as separate studies for different analyses. Only one biospecimen type per assay type will be considered based on a predefined priority order. Samples including fewer than 10 participants or assessing infection in the upper genital tract will be excluded. Quality assessments will be conducted for all measures included in the review. Meta-analyses will be implemented using DerSimonian-Laird random effect models to estimate the mean prevalence of gonorrhoea in infertile populations globally, and stratified by WHO region, assay type, sex, infertility type, infertility diagnosis, among other factors. Detailed heterogeneity assessment will be performed, and potential sources of between-study heterogeneity will be explored using meta-regression. Review will be conducted from 26 March 2018 to 28 July 2019. An institutional review board clearance is not required as all data are publicly available. The findings will be disseminated through a peer-reviewed publication and international scientific meetings/workshops with key stakeholders. CRD42018102934.

Identifiants

pubmed: 31122971
pii: bmjopen-2018-025808
doi: 10.1136/bmjopen-2018-025808
pmc: PMC6538097
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e025808

Subventions

Organisme : World Health Organization
ID : 001
Pays : International

Informations de copyright

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

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Auteurs

Hiam Chemaitelly (H)

Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Doha, Qatar.

Manale Harfouche (M)

Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Doha, Qatar.

Karel Blondeel (K)

Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.

Thabo Christopher Matsaseng (TC)

Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.

James Kiarie (J)

Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.

Igor Toskin (I)

Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.

Laith J Abu-Raddad (LJ)

Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Doha, Qatar.
Department of Healthcare Policy and Research, Weill Cornell Medicine, New York City, New York, USA.
College of Health and Life Sciences, Hamadbin Khalifa University, Doha, Qatar.

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Classifications MeSH