Symptom reporting, healthcare-seeking behaviour and antibiotic use for common infections: protocol for Bug Watch, a prospective community cohort study.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
22 05 2019
Historique:
entrez: 25 5 2019
pubmed: 28 5 2019
medline: 30 5 2020
Statut: epublish

Résumé

Antimicrobial resistance is a significant worldwide problem largely driven by selective pressure exerted through antibiotic use. Preserving antibiotics requires identification of opportunities to safely reduce prescriptions, for example in the management of mild common infections in the community. However, more information is needed on how infections are usually managed and what proportion lead to consultation and antibiotic use. The aim of this study is to quantify consultation and prescribing patterns in the community for a range of common acute infection syndromes (respiratory, gastrointestinal, skin/soft tissue, mouth/dental, eye and urinary tract). This will inform development of interventions to improve antibiotic stewardship as part of a larger programme of work, Preserving Antibiotics through Safe Stewardship. This will be an online prospective community cohort study in England. We will invite 19 510 adults who previously took part in a nationally representative survey (the Health Survey for England) and consented to be contacted about future studies. Adults will also be asked to register their children. Data collection will consist of a baseline registration survey followed by weekly surveys sent by email for 6 months. Weekly surveys will collect information on symptoms of common infections, healthcare-seeking behaviour and use of treatments including antibiotics. We will calculate the proportions of infection syndromes that lead to General Practitioner consultation and antibiotic prescription. We will investigate how healthcare-seeking and treatment behaviours vary by demographics, social deprivation, infection profiles and knowledge and attitudes towards antibiotics, and will apply behavioural theory to investigate barriers and enablers to these behaviours. This study has been given ethical approval by the University College London Research Ethics Committee (ID 11813/001). Each participant will provide informed consent upon registration. We will disseminate our work through publication in peer-reviewed academic journals. Anonymised data will be made available through the UK Data Service (https://www.ukdataservice.ac.uk/).

Identifiants

pubmed: 31123004
pii: bmjopen-2018-028676
doi: 10.1136/bmjopen-2018-028676
pmc: PMC6537990
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e028676

Subventions

Organisme : Department of Health
ID : CS-2016-16-007
Pays : United Kingdom

Informations de copyright

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

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pubmed: 29490060
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pubmed: 21513547
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pubmed: 24717637

Auteurs

Catherine M Smith (CM)

Institute of Health Informatics, University College London, London, UK.

Anne Conolly (A)

NatCen Social Research, London, UK.

Christopher Fuller (C)

Institute of Health Informatics, University College London, London, UK.

Suzanne Hill (S)

NatCen Social Research, London, UK.

Fabiana Lorencatto (F)

Centre for Behaviour Change, University College London, London, UK.

Franziska Marcheselli (F)

NatCen Social Research, London, UK.

Susan Michie (S)

Centre for Behaviour Change, University College London, London, UK.

Jennifer S Mindell (JS)

Department of Epidemiology and Public Health, University College London, London, UK.

Matthew J Ridd (MJ)

Population Health Science Institute, University of Bristol, Bristol, UK.

Laura J Shallcross (LJ)

Institute of Health Informatics, University College London, London, UK.

Georgios Tsakos (G)

Institute of Epidemiology and Health Care, University College London, London, UK.

Andrew Hayward (A)

Institute of Epidemiology and Health Care, University College London, London, UK.

Ellen B Fragaszy (EB)

Institute of Health Informatics, University College London, London, UK.
Faculty of Epidemiology & Population Health, London School of Hygiene and Tropical Medicine, London, UK.

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Classifications MeSH