Intra-arterial chemotherapy in retinoblastoma - A paradigm change.

Retinoblastoma chemosurgery intra-arterial chemotherapy selective ophthalmic artery chemotherapy superselective ophthalmic artery chemotherapy

Journal

Indian journal of ophthalmology
ISSN: 1998-3689
Titre abrégé: Indian J Ophthalmol
Pays: India
ID NLM: 0405376

Informations de publication

Date de publication:
06 2019
Historique:
entrez: 25 5 2019
pubmed: 28 5 2019
medline: 20 8 2019
Statut: ppublish

Résumé

Intra-arterial chemotherapy (IAC), also known as superselective ophthalmic artery chemotherapy or chemosurgery, is currently widely accepted as one of the primary treatment modalities for intraocular retinoblastoma worldwide. Following the introduction of the technique in 1998, IAC has evolved over the past decades to be safer and more effective. Accumulated evidence shows that IAC is more effective in providing eye salvage in group D and E retinoblastoma as compared to conventional systemic intravenous chemotherapy (IVC). In contrast to IVC, IAC has the added benefits of reduced overall treatment duration and minimal systemic toxicity. This review provides a comprehensive update on the history, technique, indications, contraindications, and outcome of IAC. We have also identified the strengths, weaknesses, opportunities and threats (SWOT analysis) of the technique in this review.

Identifiants

pubmed: 31124482
pii: IndianJOphthalmol_2019_67_6_740_259070
doi: 10.4103/ijo.IJO_866_19
pmc: PMC6552585
doi:

Substances chimiques

Antineoplastic Agents 0

Types de publication

Journal Article Review

Langues

eng

Pagination

740-754

Commentaires et corrections

Type : ErratumIn

Déclaration de conflit d'intérêts

None

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Auteurs

Fairooz P Manjandavida (FP)

Ocular Oncology Service, HORUS Specialty Eye Care and Prabha Eye Clinic, Bangalore, India; Women's and Children's Hospital, Guangzhou, China.

Christina Stathopoulos (C)

Pediatric Ocular Oncology Service, Jules-Gonin Eye Hospital, Lausanne, Switzerland.

Jing Zhang (J)

Women's and Children's Hospital, Guangzhou, China.

Santhosh G Honavar (SG)

Ocular Oncology Service, Center for Sight, Hyderabad, India.

Carol L Shields (CL)

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.

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Classifications MeSH