In vitro cytotoxicity studies of industrial Eucalyptus kraft lignins on mouse hepatoma, melanoma and Chinese hamster ovary cells.

Animals Antineoplastic Agents, Phytogenic / chemistry Antioxidants / chemistry CHO Cells Carcinoma, Hepatocellular Cell Line, Tumor Cell Survival / drug effects Chemical Phenomena Cricetulus Eucalyptus / chemistry Lignin / chemistry Liquid-Liquid Extraction Melanoma Mice Phytochemicals / chemistry Spectrum Analysis
Antioxidant Cancerous cells Chemical structure Cytotoxicity Kraft lignin

Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
15 Aug 2019
Historique:
received: 18 03 2019
revised: 30 04 2019
accepted: 18 05 2019
pubmed: 28 5 2019
medline: 18 12 2019
entrez: 25 5 2019
Statut: ppublish

Résumé

Kraft lignin is a polyphenolic compound generated as a by-product from the kraft pulping process in large quantities annually worldwide. In addition to its commercial availability, its structural features make it worth to be considered in the pharmaceutical area. The present study was carried out to evaluate in vitro antioxidant and cytotoxic properties of kraft lignin on mouse hepatoma MH-22A, melanoma B16 (tumor cells) and Chinese hamster ovary (CHO, non-cancerous) cells. Moreover, several analytical techniques were used in order to elucidate the chemical structure of isolated industrial lignins (FT-IR, GPC, Py-GC-MS, 2D HSQC NMR). Results revealed high phenolic content in their composition, high-condensed structure and high phenolic hydroxyls group content. DPPH and ABTS

Identifiants

DOI: 10.1016/j.ijbiomac.2019.05.111 PMID: 31125648
pubmed: 31125648
pii: S0141-8130(19)32013-6
doi: 10.1016/j.ijbiomac.2019.05.111
pii:
doi:

Substances chimiques

Antineoplastic Agents, Phytogenic 0
Antioxidants 0
Phytochemicals 0
Kraft lignin 8068-05-1
Lignin 9005-53-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

353-361

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Oihana Gordobil (O)

Chemical and Environmental Engineering Department, University of the Basque Country UPV/EHU, Plaza Europa, 1, 20018 Donostia-San Sebastián, Spain.

Alona Oberemko (A)

Department of Biology, Vytautas Magnus University, Vileikos 8, 44248 Kaunas, Lithuania.

Gintautas Saulis (G)

Department of Biology, Vytautas Magnus University, Vileikos 8, 44248 Kaunas, Lithuania.

Vykintas Baublys (V)

Department of Biology, Vytautas Magnus University, Vileikos 8, 44248 Kaunas, Lithuania.

Jalel Labidi (J)

Chemical and Environmental Engineering Department, University of the Basque Country UPV/EHU, Plaza Europa, 1, 20018 Donostia-San Sebastián, Spain. Electronic address: jalel.labidi@ehu.es.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Antinéoplasiques d'origine végétale › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Antioxydants › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules CHO › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Tumeurs du foie › Carcinome hépatocellulaire › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Phénomènes chimiques › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Cricetulus › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Myrtaceae › Eucalyptus › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Biopolymères › Lignine › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Fractionnement chimique › Extraction liquide-liquide › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Naevus et mélanomes › Mélanome › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Facteurs biologiques › Composés phytochimiques › In vitro cytotoxicity studies of industrial...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › In vitro cytotoxicity studies of industrial...