The small non-coding RNA profile of mouse oocytes is modified during aging.

Aging / metabolism Animals Female Gene Expression Profiling Mice Microtubule-Associated Proteins / metabolism Oocytes / metabolism RNA, Small Untranslated / metabolism beta Karyopherins / metabolism
aneuploidy endo-siRNA kinesin maternal aging meiosis miRNA oocyte small non-coding RNA

Journal

Aging
ISSN: 1945-4589
Titre abrégé: Aging (Albany NY)
Pays: United States
ID NLM: 101508617

Informations de publication

Date de publication:
24 05 2019
Historique:
received: 14 02 2019
accepted: 29 04 2019
pubmed: 28 5 2019
medline: 18 6 2020
entrez: 26 5 2019
Statut: ppublish

Résumé

Oocytes are reliant on messenger RNA (mRNA) stores to support their survival and integrity during a protracted period of transcriptional dormancy as they await ovulation. Oocytes are, however, known to experience an age-associated alteration in mRNA transcript abundance, a phenomenon that contributes to reduced developmental potential. Here we have investigated whether the expression profile of small non-protein-coding RNAs (sRNAs) is similarly altered in aged mouse oocytes. The application of high throughput sequencing revealed substantial changes to the global sRNA profile of germinal vesicle stage oocytes from young (4-6 weeks) and aged mice (14-16 months). Among these, 160 endogenous small-interfering RNAs (endo-siRNAs) and 10 microRNAs (miRNAs) were determined to differentially accumulate within young and aged oocytes. Further, we revealed decreased expression of two members of the kinesin protein family,

Identifiants

DOI: 10.18632/aging.101947 PMID: 31128574 PMC: PMC6555462
pubmed: 31128574
pii: 101947
doi: 10.18632/aging.101947
pmc: PMC6555462
doi:

Substances chimiques

KIFC5 protein, mouse 0
Kifc1 protein, mouse 0
Microtubule-Associated Proteins 0
RNA, Small Untranslated 0
beta Karyopherins 0

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2968-2997

Références

Nat Cell Biol. 2009 Jun;11(6):717-23
pubmed: 19430467
Nat Cell Biol. 2009 Jun;11(6):724-30
pubmed: 19430466
BMC Dev Biol. 2011 May 06;11:25
pubmed: 21548929
J Cell Biol. 2010 May 3;189(3):465-80
pubmed: 20439998
Nat Methods. 2012 Mar 04;9(4):357-9
pubmed: 22388286
Mol Biol Cell. 2012 Oct;23(20):3970-81
pubmed: 22918942
Biol Reprod. 2014 Aug;91(2):39
pubmed: 24990804
Mol Reprod Dev. 2017 Jan;84(1):6-7
pubmed: 27935143
J Biol Chem. 2018 Dec 7;293(49):18944-18964
pubmed: 30305393
Curr Biol. 2010 Feb 9;20(3):265-70
pubmed: 20116252
Dev Biol. 2004 Dec 15;276(2):237-52
pubmed: 15581862
Genes Dev. 2007 Mar 15;21(6):644-8
pubmed: 17369397
J Reprod Dev. 2010 Oct;56(5):502-7
pubmed: 20562521
Oxid Med Cell Longev. 2017;2017:4015874
pubmed: 29312475
RNA Biol. 2010 Sep-Oct;7(5):559-63
pubmed: 21037419
Curr Biol. 2010 Sep 14;20(17):1511-21
pubmed: 20817533
Genome Biol. 2009;10(3):R25
pubmed: 19261174
Aging (Albany NY). 2018 Feb 5;10(2):162-163
pubmed: 29410392
J Cell Biol. 1996 Jul;134(2):455-64
pubmed: 8707829
PLoS One. 2017 Jan 3;12(1):e0169213
pubmed: 28046124
Nucleic Acids Res. 2012 May;40(10):4288-97
pubmed: 22287627
Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7004-11
pubmed: 11416179
Dev Cell. 2017 Aug 21;42(4):316-332
pubmed: 28829942
Dev Biol. 2008 Apr 15;316(2):397-407
pubmed: 18342300
Epigenetics Chromatin. 2009 Aug 10;2(1):9
pubmed: 19664249
Reproduction. 2015 Dec;150(6):485-96
pubmed: 26399853
Sci Rep. 2017 Jul 24;7(1):6247
pubmed: 28740075
Genes Dev. 2007 Mar 15;21(6):682-93
pubmed: 17369401
J Cell Sci. 1983 Jul;62:301-18
pubmed: 6413518
J Cell Sci. 1992 Mar;101 ( Pt 3):547-59
pubmed: 1522143
Mol Cell. 2007 Mar 9;25(5):635-46
pubmed: 17349952
Biol Reprod. 2012 Jan 10;86(1):1-7
pubmed: 21957193
Mol Biol Cell. 2009 Mar;20(5):1348-59
pubmed: 19116309
Reprod Biomed Online. 2007 Jun;14(6):700-8
pubmed: 17579982
Biol Reprod. 2010 May;82(5):1008-17
pubmed: 20075394
EMBO Rep. 2018 Feb;19(2):368-381
pubmed: 29330318
Hum Reprod Update. 2017 Jul 1;23(4):409-420
pubmed: 28431155
PLoS Genet. 2015 Feb 19;11(2):e1005013
pubmed: 25695507
J Cell Biol. 1997 Jun 16;137(6):1321-36
pubmed: 9182665
Bioinformatics. 2010 Jan 1;26(1):139-40
pubmed: 19910308
Nature. 2008 May 22;453(7194):534-8
pubmed: 18404147
Biol Reprod. 2016 Dec;95(6):131
pubmed: 28007692
Reproduction. 2014 Jul;148(1):55-72
pubmed: 24686459
Reprod Biol Endocrinol. 2011 Mar 29;9:40
pubmed: 21447182
Hum Reprod. 2011 Apr;26(4):878-84
pubmed: 21233109
Clin Exp Pharmacol Physiol. 2014 Feb;41(2):147-53
pubmed: 24341287
PLoS One. 2015 Aug 13;10(8):e0135605
pubmed: 26270822
Mol Biol Cell. 2009 Dec;20(23):4951-61
pubmed: 19812249
Curr Biol. 2010 Feb 9;20(3):271-7
pubmed: 20116247
Hum Mol Genet. 2004 Oct 1;13(19):2263-78
pubmed: 15317747
Hum Reprod. 2014 Sep;29(9):2006-17
pubmed: 24963165
J Cell Sci. 2005 Apr 15;118(Pt 8):1745-55
pubmed: 15797926
Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12319-24
pubmed: 21730149
Nat Commun. 2017 May 18;8:15346
pubmed: 28516917
Biol Reprod. 2016 Feb;94(2):39
pubmed: 26764348
PLoS One. 2013 Sep 27;8(9):e76114
pubmed: 24086699
Nature. 2008 May 22;453(7194):539-43
pubmed: 18404146
PLoS One. 2017 Jan 26;12(1):e0170650
pubmed: 28125646
Methods Mol Biol. 2013;957:91-106
pubmed: 23138946
Genes Dev. 2006 Jul 1;20(13):1732-43
pubmed: 16766679
J Mol Biol. 1990 Oct 5;215(3):403-10
pubmed: 2231712
J Cell Biol. 1999 Oct 18;147(2):351-66
pubmed: 10525540
ACS Chem Biol. 2013 Oct 18;8(10):2201-8
pubmed: 23895133

Auteurs

Bettina P Mihalas (BP)

Priority Research Centre for Reproductive Science, Schools of Environmental and Life Sciences and Biomedical Science and Pharmacy, the University of Newcastle, Callaghan, New South Wales 2308, Australia.
Pregnancy and Reproduction Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales 2305, Australia.

Nicole J Camlin (NJ)

Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21218, United States.

Miguel J Xavier (MJ)

Priority Research Centre for Reproductive Science, Schools of Environmental and Life Sciences and Biomedical Science and Pharmacy, the University of Newcastle, Callaghan, New South Wales 2308, Australia.

Alexandra E Peters (AE)

Priority Research Centre for Reproductive Science, Schools of Environmental and Life Sciences and Biomedical Science and Pharmacy, the University of Newcastle, Callaghan, New South Wales 2308, Australia.
Pregnancy and Reproduction Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales 2305, Australia.

Janet E Holt (JE)

Priority Research Centre for Reproductive Science, Schools of Environmental and Life Sciences and Biomedical Science and Pharmacy, the University of Newcastle, Callaghan, New South Wales 2308, Australia.

Jessie M Sutherland (JM)

Priority Research Centre for Reproductive Science, Schools of Environmental and Life Sciences and Biomedical Science and Pharmacy, the University of Newcastle, Callaghan, New South Wales 2308, Australia.
Pregnancy and Reproduction Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales 2305, Australia.

Eileen A McLaughlin (EA)

Priority Research Centre for Reproductive Science, Schools of Environmental and Life Sciences and Biomedical Science and Pharmacy, the University of Newcastle, Callaghan, New South Wales 2308, Australia.
Pregnancy and Reproduction Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales 2305, Australia.
School of Biological Sciences, University of Auckland, Auckland 1142, New Zealand.
School of Science, the University of Canberra, Bruce, Australian Capital Territory 2617, Australia.

Andrew L Eamens (AL)

School of Environmental and Life Sciences, the University of Newcastle, Callaghan, New South Wales 2308, Australia.

Brett Nixon (B)

Priority Research Centre for Reproductive Science, Schools of Environmental and Life Sciences and Biomedical Science and Pharmacy, the University of Newcastle, Callaghan, New South Wales 2308, Australia.
Pregnancy and Reproduction Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales 2305, Australia.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Vieillissement › The small non-coding RNA profile of mouse...
questionsmedicales.fr › Eucaryotes › Animaux › The small non-coding RNA profile of mouse...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de profil d'expression de gènes › The small non-coding RNA profile of mouse...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › The small non-coding RNA profile of mouse...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Protéines associées aux microtubules › The small non-coding RNA profile of mouse...
questionsmedicales.fr › Cellules › Cellules germinales › Ovocytes › The small non-coding RNA profile of mouse...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › Petit ARN non traduit › The small non-coding RNA profile of mouse...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines nucléaires › Caryophérines › Caryophérines bêta › The small non-coding RNA profile of mouse...