Why we scratch: Function and dysfunction.

evolution inflammatory skin diseases itch pathogenesis pleasure scratch

Journal

Experimental dermatology
ISSN: 1600-0625
Titre abrégé: Exp Dermatol
Pays: Denmark
ID NLM: 9301549

Informations de publication

Date de publication:
12 2019
Historique:
received: 07 04 2019
revised: 17 05 2019
accepted: 21 05 2019
pubmed: 28 5 2019
medline: 29 10 2020
entrez: 28 5 2019
Statut: ppublish

Résumé

Itch is a common sensation that drives an intense urge to scratch. Itch and scratching have persisted in humans and many other species, suggesting that they play an important role in survival. This commentary discusses the function of itch as a danger signal, why itch feels unpleasant and why we feel relief and pleasure when we scratch an itch. In addition, we explore the ways that this system becomes dysfunctional in conditions of chronic itch and important implications for treatment.

Identifiants

pubmed: 31132174
doi: 10.1111/exd.13977
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1482-1484

Informations de copyright

© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

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Auteurs

Kristen M Sanders (KM)

Dr Phillip Frost Department of Dermatology and Cutaneous Surgery and Miami Itch Center, Miller School of Medicine, University of Miami, Miami, Florida.

Katharine Fast (K)

Department of Allergy and Immunology, California Pacific Medical Center, San Francisco, California.

Gil Yosipovitch (G)

Dr Phillip Frost Department of Dermatology and Cutaneous Surgery and Miami Itch Center, Miller School of Medicine, University of Miami, Miami, Florida.

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