Bilateral anterior elevation prosthesis boosts chondrocytes proliferation in mice mandibular condyle.
biomechanics
cartilage
chondrocytes
occlusion
temporomandibular joint
Journal
Oral diseases
ISSN: 1601-0825
Titre abrégé: Oral Dis
Pays: Denmark
ID NLM: 9508565
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
04
12
2018
revised:
25
03
2019
accepted:
09
05
2019
pubmed:
28
5
2019
medline:
31
12
2019
entrez:
28
5
2019
Statut:
ppublish
Résumé
We aimed to develop a mouse model predominating in a proliferative response in the articular cartilage of the temporomandibular joints. Bilateral anterior elevation of occlusion was developed by installing metal tubes onto the incisors of mice with edge-to-edge relation to prevent tooth wear, leading to an increase in the vertical height of the dental occlusion with time. Morphological changes and expression changes in Cyclin D1, Aggrecan, and type II and type X collagen in the mandibular condylar cartilage were detected. In addition, cells were isolated from the mandibular condylar cartilage and exposed to cyclic tensile strain (CTS). Compared with age-matched controls, the tooth length was longer at 3 weeks, 7 weeks, and 11 weeks in BAE mice (p < 0.05), with increased condylar cartilage thickness, matrix amount, and cell number (p < 0.05). Compared with the deep zone cells, CTS stimulated the superficial zone cells to express a higher level of proliferating cell nuclear antigen, Cyclin D1, Aggrecan, and type II collagen but a lower level of type X collagen and alkaline phosphatase. Bilateral anterior elevation stimulated the proliferative response in the mandibular condylar cartilage, offering a new therapeutic strategy for cartilage degeneration.
Substances chimiques
Dental Implants
0
Types de publication
Journal Article
Langues
eng
Pagination
1589-1599Subventions
Organisme : National Natural Science Foundation of China
ID : 81530033
Organisme : National Natural Science Foundation of China
ID : 81371166
Organisme : National Natural Science Foundation of China
ID : 81700995
Organisme : National Natural Science Foundation of China
ID : 81500875
Organisme : National Natural Science Foundation of China
ID : 81500896
Informations de copyright
© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved.
Références
Akagawa, Y., Nikai, H., & Tsuru, H. (1983). Histologic changes in rat masticatory muscles subsequent to experimental increase of the occlusal vertical dimension. Journal of Prosthetic Dentistry, 50, 725-732.
Arokoski, J., Kiviranta, I., Jurvelin, J., Tammi, M., & Helminen, H. J. (1993). Long-distance running causes site-dependent decrease of cartilage glycosaminoglycan content in the knee joints of beagle dogs. Arthritis and Rheumatism, 36, 1451-1459.
Carter, D. R., Beaupr, G. S., Marcy Wong, R., Smith, L., Andriacchi, T. P., & Schurman, D. J. (2004). The mechanobiology of articular cartilage development and degeneration. Clinical Orthopaedics and Related Research, 427, S69-S77.
Glant, T. T., Ocsko, T., Markovics, A., Szekanecz, Z., Katz, R. S., Rauch, T. A., & Mikecz, K. (2016). Characterization and localization of citrullinated proteoglycan aggrecan in human articular cartilage. PLoS ONE, 11, e0150784.
Henderson, S. E., Tudares, M. A., Tashman, S., & Almarza, A. J. (2015). Decreased temporomandibular joint range of motion in a model of early osteoarthritis in the rabbit. Journal of Oral and Maxillofacial Surgery, 73, 1695-1705.
Huey, D. J., Hu, J. C., & Athanasiou, K. A. (2012). Unlike bone, cartilage regeneration remains elusive. Science, 338, 917-921.
Hunziker, E. B., Quinn, T. M., & Hauselmann, H. J. (2002). Quantitative structural organization of normal adult human articular cartilage. Osteoarthritis Cartilage, 10, 564-572.
Intema, F., Thomas, T. P., Anderson, D. D., Elkins, J. M., Brown, T. D., Amendola, A., … Saltzman, C. L. (2011). Subchondral bone remodeling is related to clinical improvement after joint distraction in the treatment of ankle osteoarthritis. Osteoarthritis Cartilage, 19, 668-675.
Intema, F., Van Roermund, P. M., Marijnissen, A. C., Cotofana, S., Eckstein, F., Castelein, R. M., … Lafeber, F. P. (2011). Tissue structure modification in knee osteoarthritis by use of joint distraction: An open 1-year pilot study. Annals of the Rheumatic Diseases, 70, 1441-1446. https://doi.org/10.1136/ard.2010.142364
Koyama, E., Saunders, C., Salhab, I., Decker, R. S., Chen, I., Um, H., … Nah, H. D. (2014). Lubricin is required for the structural integrity and post-natal maintenance of TMJ. Journal of Dental Research, 93, 663-670.
Kuroda, S., Tanimoto, K., Izawa, T., Fujihara, S., Koolstra, J. H., & Tanaka, E. (2009). Biomechanical and biochemical characteristics of the mandibular condylar cartilage. Osteoarthritis Cartilage, 17, 1408-1415.
Kuzmanovic Pficer, J., Dodic, S., Lazic, V., Trajkovic, G., Milic, N., & Milicic, B. (2017). Occlusal stabilization splint for patients with temporomandibular disorders: Meta-analysis of short and long term effects. PLoS ONE, 12, e0171296.
Li, Y., Zhang, Z., Wu, S., & Qiao, Y. (2010). A novel experimental design model for increasing occlusal vertical dimension. Journal of Craniofacial Surgery, 21, 450-457.
Liu, Y. D., Liao, L. F., Zhang, H. Y., Lu, L., Jiao, K., Zhang, M., … Wang, M. Q. (2014). Reducing dietary loading decreases mouse temporomandibular joint degradation induced by anterior crossbite prosthesis. Osteoarthritis Cartilage, 22, 302-312.
Lu, L., Huang, J., Zhang, X., Zhang, J., Zhang, M., Jing, L., … Wang, M. (2014). Changes of temporomandibular joint and semaphorin 4D/Plexin-B1 expression in a mouse model of incisor malocclusion. Journal of Oral and Facial Pain and Headache, 28, 68-79.
Luder, H. U., Leblond, C. P., & von der Mark, K. (1988). Cellular stages in cartilage formation as revealed by morphometry, radioautography and type II collagen immunostaining of the mandibular condyle from weanling rats. The American Journal of Anatomy, 182, 197-214. https://doi.org/10.1002/aja.1001820302
Lyons, T. J., McClure, S. F., Stoddart, R. W., & McClure, J. (2006). The normal human chondro-osseous junctional region: Evidence for contact of uncalcified cartilage with subchondral bone and marrow spaces. BMC Musculoskeletal Disorders, 7, 52. https://doi.org/10.1186/1471-2474-7-52
Mao, J. J., Rahemtulla, F., & Scott, P. G. (1998). Proteoglycan expression in the rat temporomandibular joint in response to unilateral bite raise. Journal of Dental Research, 77, 1520-1528.
Mizoguchi, I., Nakamura, M., Takahashi, I., Kagayama, M., & Mitani, H. (1990). An immunohistochemical study of localization of type I and type II collagens in mandibular condylar cartilage compared with tibial growth plate. Histochemistry, 93, 593-599. https://doi.org/10.1007/BF00272201
Mizoguchi, I., Takahashi, I., Nakamura, M., Sasano, Y., Sato, S., Kagayama, M., & Mitani, H. (1996). An immunohistochemical study of regional differences in the distribution of type I and type II collagens in rat mandibular condylar cartilage. Archives of Oral Biology, 41, 863-869. https://doi.org/10.1016/S0003-9969(96)00021-0
Nowlan, N. C., Murphy, P., & Prendergast, P. J. (2007). Mechanobiology of embryonic limb development. Annals of the New York Academy of Sciences, 1101, 389-411.
Osborn, B., Bai, Y., Plaas, A. H., & Sandy, J. D. (2007). Image analysis of aggrecan degradation in articular cartilage with formalin-fixed samples. Methods in Molecular Medicine, 135, 167-182.
Shen, G., & Darendeliler, M. A. (2005). The adaptive remodeling of condylar cartilage - A transition from chondrogenesis to osteogenesis. Journal of Dental Research, 84, 691-699.
Shibata, S., Suzuki, S., Tengan, T., Ishii, M., & Kuroda, T. (1996). A histological study of the developing condylar cartilage of the fetal mouse mandible using coronal sections. Archives of Oral Biology, 41, 47-54.
Ueki, M., Tanaka, N., Tanimoto, K., Nishio, C., Honda, K., Lin, Y. Y., … Tanne, K. (2008). The effect of mechanical loading on the metabolism of growth plate chondrocytes. Annals of Biomedical Engineering, 36, 793-800.
Utreja, A., Dyment, N. A., Yadav, S., Villa, M. M., Li, Y., Jiang, X., … Rowe, D. W. (2016). Cell and matrix response of temporomandibular cartilage to mechanical loading. Osteoarthritis Cartilage, 24, 335-344.
Wang, Y. L., Zhang, J., Zhang, M., Lu, L., Wang, X., Guo, M., … Wang, M. Q. (2014). Cartilage degradation in temporomandibular joint induced by unilateral anterior crossbite prosthesis. Oral Diseases, 20, 301-306.
Wiegant, K., van Roermund, P. M., Intema, F., Cotofana, S., Eckstein, F., Mastbergen, S. C., & Lafeber, F. P. (2013). Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis. Osteoarthritis Cartilage, 21, 1660-1667.
Zhang, M., Yang, H., Lu, L., Wan, X., Zhang, J., Zhang, H., … Wang, M. (2017). Matrix replenishing by BMSCs is beneficial for osteoarthritic temporomandibular joint cartilage. Osteoarthritis Cartilage, 25, 1551-1562.