Health deficits in community dwelling adults aged 40 to 75 years.
Health status
Healthy ageing
Normal values
Screening assessments
Journal
BMC geriatrics
ISSN: 1471-2318
Titre abrégé: BMC Geriatr
Pays: England
ID NLM: 100968548
Informations de publication
Date de publication:
27 05 2019
27 05 2019
Historique:
received:
30
11
2018
accepted:
03
05
2019
entrez:
29
5
2019
pubmed:
28
5
2019
medline:
17
3
2020
Statut:
epublish
Résumé
Middle and older years are associated with age related health deficits but how early this begins and progresses is poorly understood. Better understanding is needed to address early decline and support healthier ageing outcomes. Seemingly healthy, community dwelling adults aged 40 to 75 years were recruited via local council and business networks. They completed online surveys about sleep quality, distress and physical activity, and two hours of objective testing of physiologic and anthropometric measures, mobility, cognition, grip strength, foot sensation, dexterity and functional hearing. Analysis compared outcomes for age, gender, and age and gender groups with population norms for 21 health assessments. The total number of non-compliant tests for each participant was calculated by summing the number of non-compliant tests, and the frequency of these scores across the sample was reported. Gender and age effects were tested using ANOVA models. Combined age and gender categories were used for subsequent logistic regression modelling, with females aged 40-49 years being the default comparator. Of 561 participants (67% female; mean age 60 years (SD 10.3)), everyone had at least one deficit and median deficits was 5 (IQR 2). More than 50% of participants did not meet anthropometric and exercise norms, while 30 to 40% had reduced functional hearing and cognition. Overall, men performed worse and deficits increased with age particularly for physical activity, audiology, mobility, anthropometry, oximetry and foot sensation. Heart rate, body temperature and dyspnoea were the only variables where compliance was within 95% of expected values. Multiple areas of functional decline were found in people aged in their 40s and 50s. The health deficits identified are mostly mutable hence identification and interventions to address the multi-system functional decline in people as young as 40 has the capacity to ensure healthier ageing.
Sections du résumé
BACKGROUND
Middle and older years are associated with age related health deficits but how early this begins and progresses is poorly understood. Better understanding is needed to address early decline and support healthier ageing outcomes.
METHODS
Seemingly healthy, community dwelling adults aged 40 to 75 years were recruited via local council and business networks. They completed online surveys about sleep quality, distress and physical activity, and two hours of objective testing of physiologic and anthropometric measures, mobility, cognition, grip strength, foot sensation, dexterity and functional hearing. Analysis compared outcomes for age, gender, and age and gender groups with population norms for 21 health assessments. The total number of non-compliant tests for each participant was calculated by summing the number of non-compliant tests, and the frequency of these scores across the sample was reported. Gender and age effects were tested using ANOVA models. Combined age and gender categories were used for subsequent logistic regression modelling, with females aged 40-49 years being the default comparator.
RESULTS
Of 561 participants (67% female; mean age 60 years (SD 10.3)), everyone had at least one deficit and median deficits was 5 (IQR 2). More than 50% of participants did not meet anthropometric and exercise norms, while 30 to 40% had reduced functional hearing and cognition. Overall, men performed worse and deficits increased with age particularly for physical activity, audiology, mobility, anthropometry, oximetry and foot sensation. Heart rate, body temperature and dyspnoea were the only variables where compliance was within 95% of expected values. Multiple areas of functional decline were found in people aged in their 40s and 50s.
CONCLUSIONS
The health deficits identified are mostly mutable hence identification and interventions to address the multi-system functional decline in people as young as 40 has the capacity to ensure healthier ageing.
Identifiants
pubmed: 31133002
doi: 10.1186/s12877-019-1152-9
pii: 10.1186/s12877-019-1152-9
pmc: PMC6537146
doi:
Types de publication
Journal Article
Observational Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
148Subventions
Organisme : NIMH NIH HHS
ID : R01 MH046376
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH049098
Pays : United States
Références
Age Ageing. 2011 Jul;40(4):423-9
pubmed: 21624928
Lancet. 2016 May 21;387(10033):2145-2154
pubmed: 26520231
Aust N Z J Public Health. 2001 Dec;25(6):494-7
pubmed: 11824981
Phys Ther. 2002 Feb;82(2):128-37
pubmed: 11856064
Disabil Rehabil. 2014;36(8):685-90
pubmed: 23919643
Clin Interv Aging. 2014 Mar 19;9:433-41
pubmed: 24672230
J Gerontol A Biol Sci Med Sci. 2004 Mar;59(3):255-63
pubmed: 15031310
Phys Ther. 2008 Nov;88(11):1436-43
pubmed: 19137633
Med Sci Sports Exerc. 1982;14(5):377-81
pubmed: 7154893
Eur Respir J. 2005 Aug;26(2):319-38
pubmed: 16055882
Mech Ageing Dev. 2006 May;127(5):494-6
pubmed: 16487992
J Am Geriatr Soc. 2002 Mar;50(3):530-4
pubmed: 11943052
J Chronic Dis. 1979;32(1-2):51-63
pubmed: 447779
Clin Rehabil. 2014 Nov;28(11):1078-86
pubmed: 24844238
SAGE Open Med. 2019 Jan 11;7:2050312118822440
pubmed: 30728965
J Sci Med Sport. 2011 May;14(3):233-7
pubmed: 21276752
Geriatr Gerontol Int. 2015 Feb;15(2):133-40
pubmed: 25303103
J Am Geriatr Soc. 2011 Nov;59(11):2129-38
pubmed: 22091630
Psychiatry Res. 1989 May;28(2):193-213
pubmed: 2748771
J Eval Clin Pract. 2007 Aug;13(4):689-92
pubmed: 17683315
J Am Geriatr Soc. 2017 Oct;65(10):2134-2139
pubmed: 28422280
PLoS One. 2014 Dec 04;9(12):e113637
pubmed: 25474696
Respir Med. 2006 Sep;100(9):1573-8
pubmed: 16466676