Connexin 43 Differentially Regulates Epileptiform Activity in Models of Convulsive and Non-convulsive Epilepsies.
absence epilepsy
astrocyte network
astrocyte synchronization
astrocytes
epilepsy
gap junctions
neuro-glia interaction
temporal lobe epilepsy
Journal
Frontiers in cellular neuroscience
ISSN: 1662-5102
Titre abrégé: Front Cell Neurosci
Pays: Switzerland
ID NLM: 101477935
Informations de publication
Date de publication:
2019
2019
Historique:
received:
07
12
2018
accepted:
11
04
2019
entrez:
29
5
2019
pubmed:
28
5
2019
medline:
28
5
2019
Statut:
epublish
Résumé
The influence of astrocytic cell networks on neuronal network activity is an emerging issue in epilepsy. Among the various mechanisms by which astrocytes modulate neuronal function, synchronization of astrocytes via gap junction channels is widely considered to be a crucial mechanism in epileptic conditions, contributing to the synchronization of the neuronal cell networks, possibly inducing recurrent epileptiform activity. Here, we explored whether modulation of astrocytic gap junctions could alter epileptic seizures in different types of epilepsy. Opening of gap junctions by trimethylamine intensifies seizure-like events (SLEs) in the low-[Mg
Identifiants
pubmed: 31133805
doi: 10.3389/fncel.2019.00173
pmc: PMC6523398
doi:
Types de publication
Journal Article
Langues
eng
Pagination
173Références
Brain Res. 1999 Oct 16;845(1):92-6
pubmed: 10529447
Brain Res Brain Res Rev. 2000 Apr;32(2-3):380-412
pubmed: 10760549
Neuroreport. 2000 Jul 14;11(10):2107-11
pubmed: 10923653
J Physiol. 2001 Feb 1;530(Pt 3):405-16
pubmed: 11158272
Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):495-500
pubmed: 11756680
J Neurochem. 2003 Aug;86(3):687-99
pubmed: 12859682
Glia. 2003 Sep;43(3):265-73
pubmed: 12898705
J Cell Physiol. 2003 Nov;197(2):205-13
pubmed: 14502560
J Physiol. 2003 Dec 15;553(Pt 3):729-45
pubmed: 14514879
Behav Genet. 2003 Nov;33(6):635-55
pubmed: 14574120
Trends Neurosci. 2003 Nov;26(11):610-7
pubmed: 14585601
Epilepsia. 2003 Dec;44(12):1596-600
pubmed: 14636335
Eur J Neurosci. 2004 Mar;19(5):1361-72
pubmed: 15016094
J Neurophysiol. 2004 Aug;92(2):1252-6
pubmed: 15028741
Nat Rev Neurosci. 2004 May;5(5):400-8
pubmed: 15100722
Neuroscience. 2004;129(4):1045-56
pubmed: 15561419
Neuropharmacology. 2005 Sep;49(4):551-63
pubmed: 15936783
Epilepsia. 2005 Oct;46(10):1581-91
pubmed: 16190928
Hum Mol Genet. 2005 Oct 15;14 Spec No. 2:R243-9
pubmed: 16244322
Neurobiol Dis. 2006 Jun;22(3):496-508
pubmed: 16478664
Epilepsy Res. 2006 May;69(2):119-28
pubmed: 16487682
Neuroscience. 2006 Jun 30;140(2):731-42
pubmed: 16616432
J Neurosci. 2006 May 17;26(20):5438-47
pubmed: 16707796
Trends Neurosci. 2006 Jul;29(7):391-397
pubmed: 16769131
Epilepsia. 2006 Jun;47(6):1009-22
pubmed: 16822247
J Neurochem. 2006 Nov;99(4):1049-61
pubmed: 16899068
Biochem J. 2007 Dec 15;408(3):375-85
pubmed: 17714073
Prog Neuropsychopharmacol Biol Psychiatry. 2008 Aug 1;32(6):1496-500
pubmed: 18556104
Dev Med Child Neurol. 2008 Sep;50(9):648-54
pubmed: 18754913
Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18770-5
pubmed: 19047635
Science. 2008 Dec 5;322(5907):1551-5
pubmed: 19056987
J Neurophysiol. 2009 Aug;102(2):974-8
pubmed: 19535488
PLoS One. 2009 Sep 24;4(9):e7153
pubmed: 19777062
J Neurochem. 2010 Jan;112(1):92-102
pubmed: 19840216
Brain Res Rev. 2010 May;63(1-2):212-21
pubmed: 19883685
Seizure. 2010 Oct;19(8):507-13
pubmed: 20685138
J Neurosci. 2011 Apr 27;31(17):6542-52
pubmed: 21525295
Brain Res Bull. 2011 Jul 15;85(6):410-6
pubmed: 21619914
BMC Neurosci. 2011 Oct 03;12:96
pubmed: 21967230
Glia. 2012 Aug;60(8):1203-14
pubmed: 22378467
BMC Biol. 2012 Mar 15;10:26
pubmed: 22420899
Epilepsy Curr. 2012 Mar;12(2):66-8
pubmed: 22473546
Neurosci Bull. 2012 Dec;28(6):729-36
pubmed: 23149765
Expert Rev Neurother. 2012 Dec;12(12):1419-27
pubmed: 23237349
Neurochem Int. 2013 Dec;63(7):682-7
pubmed: 23357483
Future Neurol. 2013 Mar 1;8(2):149-158
pubmed: 23658503
Synapse. 2013 Dec;67(12):839-46
pubmed: 23754322
Curr Med Chem. 2014;21(6):755-63
pubmed: 24251560
Curr Med Chem. 2014;21(6):653-62
pubmed: 24251567
Brain Res Bull. 2014 May;104:7-18
pubmed: 24704320
Cereb Cortex. 2015 Oct;25(10):3420-33
pubmed: 25037920
Neuroscience. 2016 May 26;323:157-69
pubmed: 25592426
Neuroscience. 2015 Aug 6;300:593-608
pubmed: 26037802
Front Cell Neurosci. 2015 Jun 18;9:215
pubmed: 26150770
ASN Neuro. 2015 Oct 21;7(5):null
pubmed: 26489685
J Physiol. 2016 Oct 1;594(19):5695-710
pubmed: 26940972
Biochim Biophys Acta Biomembr. 2018 Jan;1860(1):5-8
pubmed: 28559187
Sci Rep. 2017 Jul 20;7(1):6018
pubmed: 28729692
Biochim Biophys Acta Biomembr. 2018 Jan;1860(1):1-4
pubmed: 29113817
Neuron. 2018 Jun 6;98(5):935-944.e5
pubmed: 29779943
J Neurosci Res. 2018 Jul 18;:
pubmed: 30022509
Front Pharmacol. 2018 Aug 06;9:845
pubmed: 30127740
J Neurophysiol. 1987 Mar;57(3):869-88
pubmed: 3031235
Front Mol Neurosci. 2018 Dec 04;11:435
pubmed: 30564096
Front Mol Neurosci. 2019 Feb 06;12:23
pubmed: 30787868
Adv Neurol. 1986;44:641-61
pubmed: 3518350
Brain. 1997 Nov;120 ( Pt 11):1937-59
pubmed: 9397013
Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15735-40
pubmed: 9861039
J Neurosci. 1999 Jan 15;19(2):520-8
pubmed: 9880572