In vitro/in vivo hepatoprotective properties of 1-O-(4-hydroxymethylphenyl)-α-L-rhamnopyranoside from Moringa oleifera seeds against carbon tetrachloride-induced hepatic injury.
Administration, Oral
Animals
Antioxidants
/ administration & dosage
Carbon Tetrachloride
/ toxicity
Cell Line
Chemical and Drug Induced Liver Injury
/ prevention & control
Cytokines
/ metabolism
Female
Glycosides
/ administration & dosage
Liver
/ pathology
Male
Mice, Inbred ICR
Moringa oleifera
/ chemistry
Oxidative Stress
/ drug effects
Seeds
/ chemistry
1-O-(4-hydroxymethylphenyl)-α-L-rhamnopyranoside
Acute toxicity
Carbon tetrachloride
Hepatotoxicity
Moringa oleifera seeds
Oxidative stress
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
ISSN: 1873-6351
Titre abrégé: Food Chem Toxicol
Pays: England
ID NLM: 8207483
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
06
05
2019
revised:
22
05
2019
accepted:
24
05
2019
pubmed:
29
5
2019
medline:
20
8
2019
entrez:
29
5
2019
Statut:
ppublish
Résumé
1-O-(4-hydroxymethylphenyl)-α-L-rhamnopyranoside (MPG) is a phenolic glycoside that exists in Moringa oleifera seeds with various health benefits, whereas its hepatoprotective effect is lacking clarification. Herein, MPG was isolated from Moringa oleifera seeds, and its hepatoprotection against CCl
Identifiants
pubmed: 31136780
pii: S0278-6915(19)30306-0
doi: 10.1016/j.fct.2019.05.039
pii:
doi:
Substances chimiques
Antioxidants
0
Cytokines
0
Glycosides
0
Carbon Tetrachloride
CL2T97X0V0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
110531Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.