Changes in Moderate Intensity Physical Activity Are Associated With Better Cognition in the Multilevel Intervention for Physical Activity in Retirement Communities (MIPARC) Study.
Physical activity
aging
cognition
free-living environments
intervention
retirement community
Journal
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
ISSN: 1545-7214
Titre abrégé: Am J Geriatr Psychiatry
Pays: England
ID NLM: 9309609
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
received:
28
01
2019
revised:
22
04
2019
accepted:
22
04
2019
pubmed:
30
5
2019
medline:
4
9
2020
entrez:
30
5
2019
Statut:
ppublish
Résumé
The authors investigated if the physical activity increases observed in the Multilevel Intervention for Physical Activity in Retirement Communities (MIPARC) improved cognitive functions in older adults. The authors also examined if within-person changes in moderate to vigorous physical activity (MVPA), as opposed to low-light and high-light physical activity, were related to cognitive improvements in the entire sample. This was a cluster randomized control trial set in retirement communities in San Diego County, CA. A total of 307 older adults without a formal diagnosis of dementia (mean age: 83 years; age range: 67-100; standard deviation: 6.4 years; 72% women) were assigned to the physical activity (N = 151) or healthy education control (N = 156) groups. Interventions were led by study staff for the first 6 months and sustained by peer leaders for the next 6 months. Components included individual counseling and self-monitoring with pedometers, group education sessions, and printed materials. Measurements occurred at baseline, 6 months, and 12 months. Triaxial accelerometers measured physical activity for 1 week. The Trail Making Test (TMT) Parts A and B and a Symbol Search Test measured cognitive functions. There were no significant differences in cognitive functions between the MIPARC intervention and control groups at 6 or 12 months. Within-person increases in MVPA, and not low-light or high-light physical activity, were associated with improvements in TMT Parts B, B-A, and Symbol Search scores in the entire sample. Findings suggest that MVPA may have a stronger impact on cognitive functions than lower intensity physical activity within retirement community samples of highly educated older adults without dementia.
Identifiants
pubmed: 31138456
pii: S1064-7481(19)30345-8
doi: 10.1016/j.jagp.2019.04.011
pmc: PMC6739142
mid: NIHMS1528120
pii:
doi:
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1110-1121Subventions
Organisme : NIA NIH HHS
ID : K23 AG049906
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA179977
Pays : United States
Organisme : NCI NIH HHS
ID : U54 CA155435
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL111378
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL125405
Pays : United States
Organisme : NHLBI NIH HHS
ID : K23 HL119352
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2019 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.
Références
Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3316-21
pubmed: 14978288
J Mol Neurosci. 2004;24(1):9-14
pubmed: 15314244
Med Sci Sports Exerc. 2005 Nov;37(11 Suppl):S512-22
pubmed: 16294114
J Gerontol A Biol Sci Med Sci. 2006 Nov;61(11):1166-70
pubmed: 17167157
Psychol Med. 2009 Jan;39(1):3-11
pubmed: 18570697
JAMA. 2008 Sep 3;300(9):1027-37
pubmed: 18768414
J Aging Phys Act. 2008 Oct;16(4):416-34
pubmed: 19033603
J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):688-94
pubmed: 19244157
J Aging Phys Act. 2009 Jan;17(1):17-30
pubmed: 19299836
Psychosom Med. 2010 Apr;72(3):239-52
pubmed: 20223924
J Intern Med. 2011 Jan;269(1):107-17
pubmed: 20831630
Front Aging Neurosci. 2010 Aug 26;2:null
pubmed: 20890449
Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):3017-22
pubmed: 21282661
J Am Geriatr Soc. 2011 Apr;59(4):704-16
pubmed: 21438861
Front Hum Neurosci. 2011 Mar 17;5:26
pubmed: 21441997
Med Sci Sports Exerc. 2012 Jan;44(1 Suppl 1):S68-76
pubmed: 22157777
Hum Brain Mapp. 2013 Nov;34(11):2972-85
pubmed: 22674729
Contemp Clin Trials. 2012 Nov;33(6):1180-8
pubmed: 22921641
BMC Neurol. 2012 Oct 31;12:128
pubmed: 23113898
Mol Psychiatry. 2013 Aug;18(8):864-74
pubmed: 23164816
JAMA Intern Med. 2013 May 13;173(9):797-804
pubmed: 23545598
Dialogues Clin Neurosci. 2013 Mar;15(1):99-108
pubmed: 23576893
J Am Geriatr Soc. 2013 Nov;61(11):1927-31
pubmed: 24219194
Front Aging Neurosci. 2013 Nov 12;5:75
pubmed: 24282403
Clin Med Res. 2014 Sep;12(1-2):10-20
pubmed: 24415748
Int J Behav Nutr Phys Act. 2014 Mar 10;11(1):35
pubmed: 24612748
Clin Interv Aging. 2014 Aug 27;9:1425-36
pubmed: 25210447
Mol Psychiatry. 2015 May;20(5):585-93
pubmed: 25311366
Transl Psychiatry. 2014 Dec 02;4:e487
pubmed: 25463973
Curr Geriatr Rep. 2014 Dec;3(4):282-290
pubmed: 25750853
Lancet. 2015 Jun 6;385(9984):2255-63
pubmed: 25771249
PLoS One. 2015 Mar 31;10(3):e0118173
pubmed: 25826620
Cochrane Database Syst Rev. 2015 Apr 22;(4):CD005381
pubmed: 25900537
PLoS One. 2015 Jul 09;10(7):e0131647
pubmed: 26158265
JAMA. 2015 Aug 25;314(8):781-90
pubmed: 26305648
Am J Prev Med. 2016 Jan;50(1):106-110
pubmed: 26340864
Front Hum Neurosci. 2016 Jul 18;10:338
pubmed: 27462210
Front Neuroendocrinol. 2017 Jul;46:71-85
pubmed: 28442274
Front Aging Neurosci. 2017 Sep 29;9:318
pubmed: 29033829
Int J Behav Nutr Phys Act. 2018 Apr 2;15(1):32
pubmed: 29609594
J Clin Med. 2018 Sep 13;7(9):null
pubmed: 30217031
PLoS One. 2019 Jan 10;14(1):e0210036
pubmed: 30629631