Blimp1


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
28 05 2019
Historique:
received: 21 02 2019
accepted: 25 04 2019
entrez: 30 5 2019
pubmed: 30 5 2019
medline: 18 6 2019
Statut: epublish

Résumé

Most studies on the skin focus primarily on the hair follicle and interfollicular epidermis, whereas little is known regarding the homeostasis of the sebaceous gland (SG). The SG has been proposed to be replenished by different pools of hair follicle stem cells and cells that resides in the SG base, marked by Blimp1. Here, we demonstrate that single Blimp1

Identifiants

pubmed: 31138796
doi: 10.1038/s41467-019-10261-6
pii: 10.1038/s41467-019-10261-6
pmc: PMC6538623
doi:

Substances chimiques

Myc protein, mouse 0
Prdm1 protein, mouse 0
Proto-Oncogene Proteins c-myc 0
Positive Regulatory Domain I-Binding Factor 1 EC 2.1.1.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2348

Subventions

Organisme : German-Israeli Foundation for Scientific Research and Development (GIF)
ID : I-2381-412.13/2015
Pays : International
Organisme : Israel Cancer Research Fund (Israel Cancer Research Fund, Inc.)
ID : AG179017
Pays : International

Références

J Lipid Res. 2010 Nov;51(11):3377-88
pubmed: 20719760
Anal Chem. 2010 Dec 1;82(23):9818-26
pubmed: 21049934
Curr Protoc Bioinformatics. 2012 Mar;Chapter 14:Unit14.11
pubmed: 22389014
Cell. 2015 Jun 18;161(7):1700-1700.e1
pubmed: 26091044
Curr Opin Chem Biol. 2016 Feb;30:87-93
pubmed: 26673825
Science. 2013 Jul 19;341(6143):286-9
pubmed: 23788729
Science. 1974 Oct 4;186(4158):19-26
pubmed: 4607408
Methods Mol Biol. 2009;482:215-32
pubmed: 19089359
Dermatology. 2002;204(2):118-23
pubmed: 11937736
Science. 2013 Jun 7;340(6137):1190-4
pubmed: 23744940
Lancet. 2012 Jan 28;379(9813):361-72
pubmed: 21880356
Anal Chem. 2006 Feb 1;78(3):779-87
pubmed: 16448051
Int J Biochem Cell Biol. 2010 Feb;42(2):181-5
pubmed: 19944183
Curr Biol. 2001 Apr 17;11(8):558-68
pubmed: 11369200
Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6476-81
pubmed: 23576729
Cell. 2016 Jun 16;165(7):1586-1597
pubmed: 27315476
Am J Pathol. 2004 Sep;165(3):729-40
pubmed: 15331398
J Invest Dermatol. 2006 Sep;126(9):2002-9
pubmed: 16675962
J Biol Chem. 1957 May;226(1):497-509
pubmed: 13428781
J Lipid Res. 2008 Feb;49(2):271-81
pubmed: 17975220
Mol Cell. 2018 May 17;70(4):573-587.e4
pubmed: 29775577
Cell. 1998 Nov 25;95(5):605-14
pubmed: 9845363
Nature. 2007 Feb 22;445(7130):834-42
pubmed: 17314969
Nat Rev Cancer. 2018 Mar;18(3):187-201
pubmed: 29348578
Dermatology. 1998;196(1):43-6
pubmed: 9557223
Cell Stem Cell. 2013 Oct 3;13(4):471-82
pubmed: 23954751
Science. 2014 Jun 13;344(6189):1242281
pubmed: 24926024
Cell Rep. 2013 Feb 21;3(2):427-41
pubmed: 23403291
Exp Dermatol. 2013 Oct;22(10):667-9
pubmed: 24079739
Stem Cell Reports. 2014 Oct 14;3(4):620-33
pubmed: 25358790
EMBO J. 2017 Jan 17;36(2):151-164
pubmed: 27940653
Gastroenterology. 2007 Feb;132(2):587-600
pubmed: 17258732
J Vis Exp. 2016 Apr 29;(110):
pubmed: 27168117
Bioorg Med Chem Lett. 2009 Feb 1;19(3):807-10
pubmed: 19114306
Science. 2010 Mar 12;327(5971):1385-9
pubmed: 20223988
J Cell Sci. 2005 Apr 15;118(Pt 8):1693-704
pubmed: 15797928
Nat Rev Cancer. 2008 Mar;8(3):234-42
pubmed: 18292777
Hum Genet. 2014 Mar;133(3):259-64
pubmed: 24114350
Nature. 2005 Jul 14;436(7048):207-13
pubmed: 15937476
Semin Cell Dev Biol. 2012 Oct;23(8):928-36
pubmed: 22960253
Nucleic Acids Res. 2007 Jan;35(Database issue):D527-32
pubmed: 17098933
Curr Protoc Stem Cell Biol. 2017 May 16;41:1C.20.1-1C.20.11
pubmed: 28510329
Br J Dermatol. 2005 Jun;152(6):1125-33
pubmed: 15948972
Nat Rev Dis Primers. 2015 Sep 17;1:15029
pubmed: 27189872
Cell. 2006 Aug 11;126(3):597-609
pubmed: 16901790
Biochemistry. 1999 Jan 5;38(1):185-90
pubmed: 9890897
Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14988-93
pubmed: 17846422
Nat Genet. 2001 Jun;28(2):165-8
pubmed: 11381265
Microbiome. 2018 Oct 2;6(1):177
pubmed: 30285861

Auteurs

Alona Feldman (A)

Laboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Lorry Lokey Interdisciplinary Center for Life Sciences & Engineering, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Technion Integrated Cancer Center, Technion Israel Institute of Technology, 3200003, Haifa, Israel.

Dzmitry Mukha (D)

Lorry Lokey Interdisciplinary Center for Life Sciences & Engineering, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Department of Computer Science, Technion Israel Institute of Technology, 3200003, Haifa, Israel.

Itzhak I Maor (II)

Laboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Lorry Lokey Interdisciplinary Center for Life Sciences & Engineering, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Technion Integrated Cancer Center, Technion Israel Institute of Technology, 3200003, Haifa, Israel.

Egor Sedov (E)

Laboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Lorry Lokey Interdisciplinary Center for Life Sciences & Engineering, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Technion Integrated Cancer Center, Technion Israel Institute of Technology, 3200003, Haifa, Israel.

Elle Koren (E)

Laboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Lorry Lokey Interdisciplinary Center for Life Sciences & Engineering, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Technion Integrated Cancer Center, Technion Israel Institute of Technology, 3200003, Haifa, Israel.

Yahav Yosefzon (Y)

Laboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Lorry Lokey Interdisciplinary Center for Life Sciences & Engineering, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Technion Integrated Cancer Center, Technion Israel Institute of Technology, 3200003, Haifa, Israel.

Tomer Shlomi (T)

Lorry Lokey Interdisciplinary Center for Life Sciences & Engineering, Technion Israel Institute of Technology, 3200003, Haifa, Israel.
Department of Computer Science, Technion Israel Institute of Technology, 3200003, Haifa, Israel.

Yaron Fuchs (Y)

Laboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, 3200003, Haifa, Israel. yfuchs@technion.ac.il.
Lorry Lokey Interdisciplinary Center for Life Sciences & Engineering, Technion Israel Institute of Technology, 3200003, Haifa, Israel. yfuchs@technion.ac.il.
Technion Integrated Cancer Center, Technion Israel Institute of Technology, 3200003, Haifa, Israel. yfuchs@technion.ac.il.

Articles similaires

Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH