Stereotactic body radiation therapy in patients with hepatocellular carcinoma: A mini-review.

Combination approaches Hepatocellular carcinoma Local-ablative treatment Mini-review Stereotactic body radiation therapy

Journal

World journal of gastrointestinal oncology
ISSN: 1948-5204
Titre abrégé: World J Gastrointest Oncol
Pays: China
ID NLM: 101532470

Informations de publication

Date de publication:
15 May 2019
Historique:
received: 16 01 2019
revised: 14 03 2019
accepted: 27 03 2019
entrez: 30 5 2019
pubmed: 30 5 2019
medline: 30 5 2019
Statut: ppublish

Résumé

Stereotactic body radiation therapy (SBRT) is an emerging treatment for hepatocellular carcinoma. This technique results in excellent local control rates with favorable toxicity profile despite being predominantly used in heavily pretreated patients or those unsuitable for other local therapies. SBRT may be used as a sole treatment or in combination with other local therapies as well as a bridging strategy for patient awaiting liver transplants. This brief review describes current practice of SBRT with respect to radiation technique, patient selection and treatment concepts. It summarizes available evidence from retro- and prospective studies evaluating SBRT alone, SBRT in combination with other treatments and SBRT compared to other local treatment approaches.

Identifiants

pubmed: 31139307
doi: 10.4251/wjgo.v11.i5.367
pmc: PMC6522765
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

367-376

Déclaration de conflit d'intérêts

Conflict-of-interest statement: The authors have no conflicts of interest to declare.

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Auteurs

Sabine Gerum (S)

Department of Radiation Oncology, University Hospital LMU Munich, Munich, 81377, Germany.

Alexandra D Jensen (AD)

Department of Radiation Oncology, University Hospital Gießen and Marburg, Marburg, 35043, Germany.

Falk Roeder (F)

CCU Molecular Radiation Oncology, German Cancer Research Center, Heidelberg, 74626, Germany. falk.roeder@t-online.de.

Classifications MeSH