Kaposi Sarcoma-Associated Herpesvirus Glycoprotein H Is Indispensable for Infection of Epithelial, Endothelial, and Fibroblast Cell Types.
B cell
Kaposi sarcoma-associated herpesvirus
endothelial
epithelial
fibroblast
glycoprotein H
infection
mutation
tropism
viral entry
Journal
Journal of virology
ISSN: 1098-5514
Titre abrégé: J Virol
Pays: United States
ID NLM: 0113724
Informations de publication
Date de publication:
15 08 2019
15 08 2019
Historique:
received:
16
04
2019
accepted:
15
05
2019
pubmed:
31
5
2019
medline:
4
6
2020
entrez:
31
5
2019
Statut:
epublish
Résumé
Kaposi sarcoma-associated herpesvirus (KSHV) is an emerging pathogen and is the causative infectious agent of Kaposi sarcoma and two malignancies of B cell origin. To date, there is no licensed KSHV vaccine. Development of an effective vaccine against KSHV continues to be limited by a poor understanding of how the virus initiates acute primary infection
Identifiants
pubmed: 31142670
pii: JVI.00630-19
doi: 10.1128/JVI.00630-19
pmc: PMC6675886
pii:
doi:
Substances chimiques
Viral Envelope Proteins
0
glycoprotein H, human herpesvirus 8
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NCI NIH HHS
ID : K01 CA184388
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA033572
Pays : United States
Informations de copyright
Copyright © 2019 American Society for Microbiology.
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