Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome.
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
05
06
2018
accepted:
26
04
2019
pubmed:
31
5
2019
medline:
30
11
2019
entrez:
31
5
2019
Statut:
ppublish
Résumé
Herpesviruses are enveloped viruses that are prevalent in the human population and are responsible for diverse pathologies, including cold sores, birth defects and cancers. They are characterized by a highly pressurized pseudo-icosahedral capsid-with triangulation number (T) equal to 16-encapsidating a tightly packed double-stranded DNA (dsDNA) genome
Identifiants
pubmed: 31142842
doi: 10.1038/s41586-019-1248-6
pii: 10.1038/s41586-019-1248-6
pmc: PMC6732574
mid: NIHMS1528070
doi:
Substances chimiques
DNA, Viral
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
257-261Subventions
Organisme : NIAID NIH HHS
ID : R01 AI094386
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE028583
Pays : United States
Organisme : NCRR NIH HHS
ID : S10 RR023057
Pays : United States
Organisme : NIGMS NIH HHS
ID : U24 GM116792
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE025567
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM071940
Pays : United States
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