Effect of ointment-based egg white on healing of second- degree wound in burn patients: a triple-blind randomized clinical trial study.
Burn
Egg white
Patient
Silver sulfadiazine
Traditional medicine
Journal
Avicenna journal of phytomedicine
ISSN: 2228-7930
Titre abrégé: Avicenna J Phytomed
Pays: Iran
ID NLM: 101586220
Informations de publication
Date de publication:
Historique:
entrez:
31
5
2019
pubmed:
31
5
2019
medline:
31
5
2019
Statut:
ppublish
Résumé
Burn wound healing is one of the problems of medical sciences and it is of great importance to find a drug or substance that can heal burn wounds with minimum complications. The present study aimed to evaluate the effect of ointment-based egg white on healing second-degree burn wounds. In the present triple-blind clinical trial, a total of 90 patients from Taleghani hospital, Ahvaz, Iran were selected and randomly divided into two groups based on the inclusion criteria. The intervention group was dressed with egg white formulation + silver sulfadiazine cream and the control group was treated with placebo + silver sulfadiazine cream. The burn wound healing process was evaluated on days 1, 7 and 15 by the Bates-Jensen wound assessment tool. The mean scores of wound healing were decreased (13.75±1.83) in the intervention group when compared to the control (21.51±5.7) on day 15 (p<0.001). The mean duration of wound healing, wound depth, edges, undermining, necrotic tissue, amount of necrosis, exudate type and amount, surrounding skin color, wound induration, peripheral edema, granulation, and epithelialization were significantly decrease in intervention group in comparison with control (p<0.001). The findings of this research showed that egg whites formulation is an appropriate treatment for burn wound healing, reduced above-noted burn wounds' variables. It seems that this treatment, along with the common medicine, improves chronic wound recovery rate and patients' health status.
Types de publication
Journal Article
Langues
eng
Pagination
260-270Déclaration de conflit d'intérêts
The authors have no conflict of interest. This article was approved by both academic and clinical institutional review board. All performed procedures in the present study have been done in accordance to the Ethical Committee of Ahvaz Jundishapur University of Medical Sciences with No. IR.AJUMS.REC.1396.146. Also, the Clinical Trials Code of this research was IRCT2017053134262N1, and conducted in accordance to Helsinki Declaration of 1975, revised in 2000.
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