Intracervical elastomeric sealant in an

Elastomeric sealant fibrin glue fluid leakage premature rupture of membranes uterine cervix

Journal

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
ISSN: 1476-4954
Titre abrégé: J Matern Fetal Neonatal Med
Pays: England
ID NLM: 101136916

Informations de publication

Date de publication:
Apr 2021
Historique:
pubmed: 31 5 2019
medline: 22 6 2021
entrez: 1 6 2019
Statut: ppublish

Résumé

Premature rupture of membranes occurring in previable midtrimester patients is associated with perinatal mortality, and optimal therapeutic methods are yet to be established. This study's objective was to investigate whether an elastomeric sealant, which has been used as a hemostatic agent for arterial anastomosis, could plug the uterine endocervical canal to prevent leakage of intrauterine fluid in an The elastomeric sealant or fibrin glue was applied to the cervix of uteri removed for benign gynecological disease ( No fluid leakage was observed with the elastomeric sealant until the pressure exceeded 20 kPa (150 mmHg), while the leakage onset pressure with fibrin sealant was 6.6 ± 1.8 kPa (50 ± 14 mmHg). The threshold leak pressure where the onset of liquid flow was initiated was significantly different between both the sealants ( Intracervical elastomeric sealant exhibited powerful fluid leakage prevention in an

Sections du résumé

BACKGROUND BACKGROUND
Premature rupture of membranes occurring in previable midtrimester patients is associated with perinatal mortality, and optimal therapeutic methods are yet to be established.
OBJECTIVE OBJECTIVE
This study's objective was to investigate whether an elastomeric sealant, which has been used as a hemostatic agent for arterial anastomosis, could plug the uterine endocervical canal to prevent leakage of intrauterine fluid in an
METHODS METHODS
The elastomeric sealant or fibrin glue was applied to the cervix of uteri removed for benign gynecological disease (
RESULTS RESULTS
No fluid leakage was observed with the elastomeric sealant until the pressure exceeded 20 kPa (150 mmHg), while the leakage onset pressure with fibrin sealant was 6.6 ± 1.8 kPa (50 ± 14 mmHg). The threshold leak pressure where the onset of liquid flow was initiated was significantly different between both the sealants (
CONCLUSIONS CONCLUSIONS
Intracervical elastomeric sealant exhibited powerful fluid leakage prevention in an

Identifiants

pubmed: 31146608
doi: 10.1080/14767058.2019.1626367
doi:

Substances chimiques

Fibrin Tissue Adhesive 0
Tissue Adhesives 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1109-1111

Auteurs

Eiji Kondoh (E)

Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan.

Yosuke Kawamura (Y)

Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan.

Yoshitsugu Chigusa (Y)

Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan.

Haruta Mogami (H)

Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan.

Akihiko Ueda (A)

Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan.

Junzo Hamanishi (J)

Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan.

Masaki Mandai (M)

Department of Gynecology and Obstetrics, Kyoto University, Kyoto, Japan.

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Classifications MeSH