Transplantation of Autologous Dermo-Epidermal Skin Substitutes in a Pig Model.

Animals Dermis Epidermis Models, Animal Regenerative Medicine / methods Skin Transplantation / methods Skin, Artificial Sus scrofa / surgery Tissue Engineering Transplantation, Autologous / methods
Animal model Dermo-epidermal skin substitute Perioperative refinement Pig Skin transplantation

Journal

Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969

Informations de publication

Date de publication:
2019
Historique:
entrez: 1 6 2019
pubmed: 31 5 2019
medline: 27 2 2020
Statut: ppublish

Résumé

Due to its similarity of skin anatomy and physiology, the pig appears to be a well-suited animal model for preclinical studies of skin analog transplantations. The choice of the location of the skin defect and appropriate postoperative measures are essential for the protection of the transplanted graft. This protocol describes in detail a porcine skin transplantation model including peri- and postoperative measures taken to improve and refine the study outcome.

Identifiants

DOI: 10.1007/978-1-4939-9473-1_20 PMID: 31148093
pubmed: 31148093
doi: 10.1007/978-1-4939-9473-1_20
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

251-259

Références

Sullivan TP, Eaglstein WH, Davis SC, Mertz P (2001) The pig as a model for human wound healing. Wound Repair Regen 9(2):66–76
doi: 10.1046/j.1524-475x.2001.00066.x
Lindblad WJ (2008) Considerations for selecting the correct animal model for dermal wound-healing studies. J Biomater Sci Polym Ed 19(8):1087–1096
doi: 10.1163/156856208784909390
Swindle MM, Makin A, Herron AJ, Clubb FJ Jr, Frazier KS (2012) Swine as models in biomedical research and toxicology testing. Vet Pathol 49(2):344–356
doi: 10.1177/0300985811402846
Bottcher-Haberzeth S, Biedermann T, Reichmann E (2010) Tissue engineering of skin. Burns 36(4):450–460
doi: 10.1016/j.burns.2009.08.016
Schiestl C, Biedermann T, Braziulis E, Hartmann-Fritsch F, Böttcher-Haberzeth S, Arras M, Cesarovic N, Nicolls F, Linti C, Reichmann E, Meuli M (2011) Skingineering II: transplantation of large-scale laboratory-grown skin analogues in a new pig model. Pediatr Surg Int 27:249–254
doi: 10.1007/s00383-010-2792-1

Auteurs

Thea Fleischmann (T)

Division of Surgical Research, University Hospital Zurich, University of Zurich, Zurich, Switzerland. thea.fleischmann@usz.ch.
Biological Central Laboratory, University of Zurich, Zurich, Switzerland. thea.fleischmann@usz.ch.

Flora Nicholls (F)

Biological Central Laboratory, University of Zurich, Zurich, Switzerland.

Miriam Lipiski (M)

Division of Surgical Research, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Biological Central Laboratory, University of Zurich, Zurich, Switzerland.

Margarete Arras (M)

Division of Surgical Research, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Nikola Cesarovic (N)

Division of Surgical Research, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Transplantation of Autologous Dermo-Epidermal...
questionsmedicales.fr › Système tégumentaire › Peau › Derme › Transplantation of Autologous Dermo-Epidermal...
questionsmedicales.fr › Système tégumentaire › Peau › Épiderme › Transplantation of Autologous Dermo-Epidermal...
questionsmedicales.fr › Techniques d'investigation › Modèles animaux › Transplantation of Autologous Dermo-Epidermal...
questionsmedicales.fr › Professions de santé › Médecine › Médecine régénérative › Transplantation of Autologous Dermo-Epidermal...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation de tissu › Transplantation de peau › Transplantation of Autologous Dermo-Epidermal...
questionsmedicales.fr › Équipement et fournitures › Équipement chirurgical › Organes artificiels › Peau artificielle › Transplantation of Autologous Dermo-Epidermal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › Sus scrofa › Transplantation of Autologous Dermo-Epidermal...
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Bioingénierie › Ingénierie cellulaire › Ingénierie tissulaire › Transplantation of Autologous Dermo-Epidermal...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation autologue › Transplantation of Autologous Dermo-Epidermal...