Apremilast Coadministered with Secukinumab for Safe and Effective Control of Psoriasis with Resultant Reduction of Maintenance Dose of the Biologic.
Apremilast
psoriasis
secukinumab
Journal
Indian journal of dermatology
ISSN: 1998-3611
Titre abrégé: Indian J Dermatol
Pays: India
ID NLM: 0370750
Informations de publication
Date de publication:
Historique:
entrez:
1
6
2019
pubmed:
1
6
2019
medline:
1
6
2019
Statut:
ppublish
Résumé
Psoriasis is a chronic immune-mediated inflammatory condition, affecting 2-3% of the population. In recent years, advent of biologics, including secukinumab, have been a major advancement in the management of difficult-to-treat plaque psoriasis. However, high cost of biologics is often a deterrent, especially for Indian socioeconomic condition. Apremilast is an oral phosphodiesterase 4 inhibitor that is safe for use along with many other systemic therapies of psoriasis, including biologics. We report two cases of psoriasis on secukinumab therapy for long duration with good response to therapy. Later, addition of apremilast, allowed halving the dose of secukinumab with maintenance of improvement.
Identifiants
pubmed: 31148865
doi: 10.4103/ijd.IJD_548_18
pii: IJD-64-239
pmc: PMC6537682
doi:
Types de publication
Case Reports
Langues
eng
Pagination
239-241Déclaration de conflit d'intérêts
There are no conflicts of interest.
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