Differentiation between Luminal A and B Molecular Subtypes of Breast Cancer Using Pharmacokinetic Quantitative Parameters with Histogram and Texture Features on Preoperative Dynamic Contrast-Enhanced Magnetic Resonance Imaging.
Biomarkers
Breast cancer
Magnetic resonance imaging
Molecular subtype
Journal
Academic radiology
ISSN: 1878-4046
Titre abrégé: Acad Radiol
Pays: United States
ID NLM: 9440159
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
21
03
2019
revised:
22
04
2019
accepted:
01
05
2019
pubmed:
4
6
2019
medline:
11
11
2020
entrez:
2
6
2019
Statut:
ppublish
Résumé
The aim of the present study was to use pharmacokinetic quantitative parameters with histogram and texture features on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to differentiate between the luminal A and luminal B molecular subtypes of breast cancer. We retrospectively reviewed the data of 94 patients with histopathologically proven breast cancer. The pharmacokinetic quantitative parameters (K The maximum values of K Pharmacokinetic quantitative parameters with histogram and texture features obtained from DCE-MRI are associated with the molecular subtypes of breast cancer, and may serve as potential imaging biomarkers to differentiate between the luminal A and luminal B molecular subtypes.
Identifiants
pubmed: 31151899
pii: S1076-6332(19)30223-5
doi: 10.1016/j.acra.2019.05.002
pii:
doi:
Substances chimiques
Contrast Media
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e35-e44Informations de copyright
Copyright © 2019 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.