Psychiatric disorders as risk factors for the development of type 2 diabetes mellitus: an umbrella review protocol.
diabetes mellitus
mental disorders
risk factors
umbrella review
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
30 05 2019
30 05 2019
Historique:
entrez:
2
6
2019
pubmed:
4
6
2019
medline:
10
5
2020
Statut:
epublish
Résumé
Numerous longitudinal studies, systematic reviews and meta-analyses have examined psychiatric disorders as risk factors for the development of type 2 diabetes mellitus. A more comprehensive overview of the area is warranted to summarise current evidence and discuss strengths and weaknesses to guide future research. The aim of this umbrella review is to determine whether and to what extent different psychiatric disorders are associated with the development of type 2 diabetes mellitus. Furthermore, the umbrella review also assesses the evidence on potential mediating mechanisms. The present umbrella review will consist of a comprehensive systematic search of published systematic reviews and meta-analyses of observational longitudinal studies investigating whether a psychiatric disorder is associated with the risk of developing type 2 diabetes. PubMed, Embase, PsychINFO and the Cochrane Database of Systematic Reviews will be searched, and the results will be screened for inclusion by two independent reviewers. Furthermore, the reference lists of included publications will be manually searched. Two independent reviewers will extract data and assess the methodological quality in the included systematic reviews and meta-analyses. Evidence on potential mediating mechanisms included in the systematic reviews and meta-analyses will also be reviewed. The implications of the overview will be discussed in light of the quality of the included studies, and suggestions for clinical practice and future research will be made. Ethical approval is not required for this umbrella review. Our review will be submitted for publication in a peer-reviewed international journal using open access option if available. The results will also be disseminated at international conferences. CRD42018096362.
Identifiants
pubmed: 31152031
pii: bmjopen-2018-024981
doi: 10.1136/bmjopen-2018-024981
pmc: PMC6549739
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e024981Subventions
Organisme : Medical Research Council
ID : MR/R024227/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : K013351
Pays : United Kingdom
Organisme : Medical Research Council
ID : S011676
Pays : United Kingdom
Organisme : Medical Research Council
ID : R024227
Pays : United Kingdom
Informations de copyright
© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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