Transport carrier tethering - how vesicles are captured by organelles.
Journal
Current opinion in cell biology
ISSN: 1879-0410
Titre abrégé: Curr Opin Cell Biol
Pays: England
ID NLM: 8913428
Informations de publication
Date de publication:
08 2019
08 2019
Historique:
received:
30
01
2019
revised:
16
04
2019
accepted:
24
04
2019
pubmed:
4
6
2019
medline:
2
4
2020
entrez:
3
6
2019
Statut:
ppublish
Résumé
All cells contain numerous membrane-bound organelles that carry out specific functions. These compartments do not, however, act in isolation. Some are in direct contact via membrane contact sites, while others exchange material via specific vesicles or tubular carriers laden with cargo. The term tethering in the context of this review is used to describe the primary recognition and docking of transport carriers with acceptor organelles that occurs before SNARE engagement and membrane fusion. However, it is important to note that other tethering events occur, for example, between organelles in direct contact, which do not lead to fusion.
Identifiants
pubmed: 31154044
pii: S0955-0674(18)30142-X
doi: 10.1016/j.ceb.2019.04.010
pii:
doi:
Substances chimiques
SNARE Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
140-146Subventions
Organisme : Medical Research Council
ID : MC_U105178783
Pays : United Kingdom
Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.