Quaternary ammonium compound as antimicrobial agent in resin-based sealants.


Journal

Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115

Informations de publication

Date de publication:
Feb 2020
Historique:
received: 25 06 2018
accepted: 27 05 2019
pubmed: 4 6 2019
medline: 28 2 2020
entrez: 3 6 2019
Statut: ppublish

Résumé

The aim of this study was to evaluate the influence of [2-(methacryloyloxy)ethyl] trimethylammonium chloride (METAC) in the physico-chemical properties, antibacterial activity and cytotoxicity of an experimental resin-based sealant. An experimental resin-based sealant was formulated with dimethacrylates and a photoinitiator system. METAC was added at 2.5 wt.% (G The experimental resin-based sealants presented different polymerization behaviours without significant differences in the DC (p > 0.05). There was no significant difference for initial KHN (p > 0.05). The ΔKHN ranged from 51.62 (±3.70)% to 62.40 (±4.14)%, with higher values for G The addition of METAC provided antibacterial activity to the experimental resin-based sealant. METAC is an effective quaternary ammonium compound as an antibacterial agent for resin-based sealants without cytotoxic effects against human keratinocytes.

Identifiants

pubmed: 31154540
doi: 10.1007/s00784-019-02971-4
pii: 10.1007/s00784-019-02971-4
doi:

Substances chimiques

Anti-Bacterial Agents 0
Dental Materials 0
Pit and Fissure Sealants 0
Quaternary Ammonium Compounds 0

Types de publication

Journal Article

Langues

eng

Pagination

777-784

Subventions

Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
ID : Finance Code 001

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Auteurs

Isadora Martini Garcia (IM)

Dental Materials Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil.

Stéfani Becker Rodrigues (SB)

Dental Materials Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil.

Gabriela de Souza Balbinot (G)

Dental Materials Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil.

Fernanda Visioli (F)

Laboratory of Pathology, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil.

Vicente Castelo Branco Leitune (VCB)

Dental Materials Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil.

Fabrício Mezzomo Collares (FM)

Dental Materials Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil. fabricio.collares@ufrgs.br.

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Classifications MeSH