Atypical Chemokine Receptor 3 Generates Guidance Cues for CXCL12-Mediated Endothelial Cell Migration.
Animals
Animals, Genetically Modified
CHO Cells
COS Cells
Cell Movement
/ genetics
Chemokine CXCL12
/ metabolism
Chlorocebus aethiops
Cricetulus
Embryonic Development
/ genetics
Endothelial Cells
/ metabolism
Gene Knockdown Techniques
Human Umbilical Vein Endothelial Cells
Humans
Neovascularization, Physiologic
/ genetics
Receptors, CXCR
/ genetics
Signal Transduction
/ genetics
Transfection
Zebrafish
/ embryology
ackr3b
angiogenesis
chemokine receptor
endothelial cell guidance
zebrafish
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2019
2019
Historique:
received:
25
01
2019
accepted:
29
04
2019
entrez:
4
6
2019
pubmed:
4
6
2019
medline:
10
9
2020
Statut:
epublish
Résumé
Chemokine receptor CXCR4, its ligand stromal cell-derived factor-1 (CXCL12) and the decoy receptor atypical chemokine receptor 3 (ACKR3, also named CXCR7), are involved in the guidance of migrating cells in different anatomical districts. Here, we investigated the role of the
Identifiants
pubmed: 31156639
doi: 10.3389/fimmu.2019.01092
pmc: PMC6529557
doi:
Substances chimiques
ACKR3 protein, human
0
CXCL12 protein, human
0
Chemokine CXCL12
0
Receptors, CXCR
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1092Références
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