Increment in Dietary Potassium Predicts Weight Loss in the Treatment of the Metabolic Syndrome.
dietary potassium
metabolic syndrome
weight loss
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
02 Jun 2019
02 Jun 2019
Historique:
received:
29
04
2019
revised:
27
05
2019
accepted:
30
05
2019
entrez:
5
6
2019
pubmed:
5
6
2019
medline:
7
1
2020
Statut:
epublish
Résumé
In the treatment of obesity/metabolic syndrome, dietary measures traditionally focus on reducing carbohydrate/fat-related caloric intake. The possibility that changes in potassium consumption may be related to the achieved weight loss has not been previously explored. Sixty-eight participants, with a mean age of 51.6 ± 11.0 years (F/M-30/38), who fulfilled the ATPIII criteria for the metabolic syndrome (MS) were enrolled into a 1-year intensive multidisciplinary program. Nutritional recommendation consisted of a moderate low calorie/high protein Mediterranean diet. Baseline assessment included clinical and biochemical profiling, and body composition. Nutritional components were registered over 7 days before and at the end of 1 year of treatment. Mean baseline body mass index (BMI) was 35 ± 4 kg/m², which declined by 9.4 ± 0.1% after one year of combined intervention. Linear stepwise regression analysis revealed that 45% of the predicted variance of the % decline in BMI was related to increased consumption of dietary potassium (β = -0.865) and caproic acid (β = -0.423) and reduction in the consumption of dietary vitamin B6 (β = 0.542), calcium (β = 0.335), total carbohydrates (β = 0.239) and total caloric intake (β = 0.238; An increase in dietary potassium consumption is a previously unrecognized predictor of the achieved reduction in BMI in a weight-loss-oriented multidisciplinary intervention in obesity/MS. Prospective trials are underway to confirm this post-hoc finding.
Sections du résumé
BACKGROUND
BACKGROUND
In the treatment of obesity/metabolic syndrome, dietary measures traditionally focus on reducing carbohydrate/fat-related caloric intake. The possibility that changes in potassium consumption may be related to the achieved weight loss has not been previously explored.
METHODS
METHODS
Sixty-eight participants, with a mean age of 51.6 ± 11.0 years (F/M-30/38), who fulfilled the ATPIII criteria for the metabolic syndrome (MS) were enrolled into a 1-year intensive multidisciplinary program. Nutritional recommendation consisted of a moderate low calorie/high protein Mediterranean diet. Baseline assessment included clinical and biochemical profiling, and body composition. Nutritional components were registered over 7 days before and at the end of 1 year of treatment.
RESULTS
RESULTS
Mean baseline body mass index (BMI) was 35 ± 4 kg/m², which declined by 9.4 ± 0.1% after one year of combined intervention. Linear stepwise regression analysis revealed that 45% of the predicted variance of the % decline in BMI was related to increased consumption of dietary potassium (β = -0.865) and caproic acid (β = -0.423) and reduction in the consumption of dietary vitamin B6 (β = 0.542), calcium (β = 0.335), total carbohydrates (β = 0.239) and total caloric intake (β = 0.238;
CONCLUSION
CONCLUSIONS
An increase in dietary potassium consumption is a previously unrecognized predictor of the achieved reduction in BMI in a weight-loss-oriented multidisciplinary intervention in obesity/MS. Prospective trials are underway to confirm this post-hoc finding.
Identifiants
pubmed: 31159504
pii: nu11061256
doi: 10.3390/nu11061256
pmc: PMC6627830
pii:
doi:
Substances chimiques
Potassium, Dietary
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Sagol grant for the SagolCenter for the Metabolic Syndrome research
ID : None
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Circulation. 2002 Dec 17;106(25):3143-421
pubmed: 12485966
Am J Clin Nutr. 2005 May;81(5):983-9
pubmed: 15883419
J Nutr. 2009 Jun;139(6):1150-6
pubmed: 19357215
Arch Intern Med. 2010 Jan 25;170(2):126-35
pubmed: 20101007
J Hypertens. 2011 Sep;29(9):1719-30
pubmed: 21799445
Diabetologia. 2012 May;55(5):1295-303
pubmed: 22322920
Am J Clin Nutr. 2012 Sep;96(3):647-57
pubmed: 22854410
PLoS One. 2013;8(1):e55106
pubmed: 23372822
Semin Nephrol. 2013 May;33(3):248-56
pubmed: 23953802
Atherosclerosis. 2013 Sep;230(1):80-5
pubmed: 23958257
Am J Clin Nutr. 2014 May;99(5):992-8
pubmed: 24552753
Br J Nutr. 2015 Apr 28;113(8):1308-18
pubmed: 25782331
J Clin Hypertens (Greenwich). 2016 Jan;18(1):19-24
pubmed: 26408073
Nutrients. 2016 Mar 25;8(4):183
pubmed: 27023597
Diabetes Metab Res Rev. 2017 Feb;33(2):
pubmed: 27393712
Exp Clin Endocrinol Diabetes. 2017 Sep;125(8):571-576
pubmed: 28926857
Obesity (Silver Spring). 2018 Feb;26(2):442-450
pubmed: 29318759
JAMA. 1997 May 28;277(20):1624-32
pubmed: 9168293