Screening of pharmacological uses of Urtica dioica and others benefits.


Journal

Progress in biophysics and molecular biology
ISSN: 1873-1732
Titre abrégé: Prog Biophys Mol Biol
Pays: England
ID NLM: 0401233

Informations de publication

Date de publication:
01 2020
Historique:
received: 03 05 2019
revised: 22 05 2019
accepted: 29 05 2019
pubmed: 5 6 2019
medline: 18 12 2020
entrez: 5 6 2019
Statut: ppublish

Résumé

Natural products, whether pure compounds or standardized plant extracts, offer unlimited opportunities for other drug sources due to the unequaled availability of chemical diversity. Stinging Nettle (Urtica dioica) is a unique herbaceous perennial flowering plant with stinging hairs. The leaf extract of nettle was one of the herbal remedies which the experimental, clinical and trials have complemented each other. It is a very well-known plant with a wide historical background use of stems, leaves and roots. It has a long history of use as power sources such as soup or curry, and also used as fiber and a medicinal plant. Urtica dioica has traditionally been used in the control of cardiovascular disorders especially hypertension. The leaf extract of Urtica dioica has been reported to improve glucose homeostasis in vivo. Nettle root could prevent some of the effects of prostatic hyperplasia. Extracts of nettle leaf are used as anti-inflammatory remedies for rheumatoid arthritis. Urtica dioica extract significantly increased the sensitivity of breast cancer cells to paclitaxel. This article aims to review the very wide ranging of pharmacological effects of Urtica dioica extract. Articles on PuBmed between 1980 and 2019. Description and critical review of the pharmacological effects of Urtica dioica and other uses. The nettle is actually a plant with many qualities and uses. The interest in it is deserved and it is given by other studies and investigations.

Sections du résumé

BACKGROUND
Natural products, whether pure compounds or standardized plant extracts, offer unlimited opportunities for other drug sources due to the unequaled availability of chemical diversity. Stinging Nettle (Urtica dioica) is a unique herbaceous perennial flowering plant with stinging hairs. The leaf extract of nettle was one of the herbal remedies which the experimental, clinical and trials have complemented each other. It is a very well-known plant with a wide historical background use of stems, leaves and roots. It has a long history of use as power sources such as soup or curry, and also used as fiber and a medicinal plant. Urtica dioica has traditionally been used in the control of cardiovascular disorders especially hypertension. The leaf extract of Urtica dioica has been reported to improve glucose homeostasis in vivo. Nettle root could prevent some of the effects of prostatic hyperplasia. Extracts of nettle leaf are used as anti-inflammatory remedies for rheumatoid arthritis. Urtica dioica extract significantly increased the sensitivity of breast cancer cells to paclitaxel. This article aims to review the very wide ranging of pharmacological effects of Urtica dioica extract.
METHODS
Articles on PuBmed between 1980 and 2019.
RESULTS
Description and critical review of the pharmacological effects of Urtica dioica and other uses.
CONCLUSION
The nettle is actually a plant with many qualities and uses. The interest in it is deserved and it is given by other studies and investigations.

Identifiants

pubmed: 31163183
pii: S0079-6107(19)30098-7
doi: 10.1016/j.pbiomolbio.2019.05.008
pii:
doi:

Substances chimiques

Anti-Inflammatory Agents 0
Antineoplastic Agents 0
Antioxidants 0
Biological Products 0
Cardiovascular Agents 0
Plant Extracts 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

67-77

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Raouia Dhouibi (R)

Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.

Hanen Affes (H)

Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia. Electronic address: affeshanen13@yahoo.fr.

Maryem Ben Salem (M)

Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.

Serria Hammami (S)

Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.

Zouheir Sahnoun (Z)

Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.

Khaled Mounir Zeghal (KM)

Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.

Kamilia Ksouda (K)

Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH