Evaluation of a New Interface Combining High-Flow Nasal Cannula and CPAP.


Journal

Respiratory care
ISSN: 1943-3654
Titre abrégé: Respir Care
Pays: United States
ID NLM: 7510357

Informations de publication

Date de publication:
Oct 2019
Historique:
pubmed: 6 6 2019
medline: 29 7 2020
entrez: 6 6 2019
Statut: ppublish

Résumé

This study assessed the effects of a new interface that combined CPAP 10 cm H After baseline assessment during spontaneous breathing, HFNC was applied at flows of 30, 40, and 50 L/min. Successively, the volunteers underwent helmet CPAP at 10 cm H Variations of pharyngeal pressures at end-inspiration changes were small overall and clinically unimportant. With the mouth closed, at increasing HFNC flow, variations of pharyngeal pressures at end-expiration increased during both HFNC (from 2.8 up to 7.7) and, to a lesser extent, CPAP + HFNC (from 2.7 up to 3.8) ( CPAP + HFNC was well tolerated, with no adverse effects. Based on our findings, there was no need to vary the CPAP level when adding HFNC. At least in healthy subjects, CPAP + HFNC at 30 L/min seemed to be the best combination.

Sections du résumé

BACKGROUND BACKGROUND
This study assessed the effects of a new interface that combined CPAP 10 cm H
METHODS METHODS
After baseline assessment during spontaneous breathing, HFNC was applied at flows of 30, 40, and 50 L/min. Successively, the volunteers underwent helmet CPAP at 10 cm H
RESULTS RESULTS
Variations of pharyngeal pressures at end-inspiration changes were small overall and clinically unimportant. With the mouth closed, at increasing HFNC flow, variations of pharyngeal pressures at end-expiration increased during both HFNC (from 2.8 up to 7.7) and, to a lesser extent, CPAP + HFNC (from 2.7 up to 3.8) (
CONCLUSIONS CONCLUSIONS
CPAP + HFNC was well tolerated, with no adverse effects. Based on our findings, there was no need to vary the CPAP level when adding HFNC. At least in healthy subjects, CPAP + HFNC at 30 L/min seemed to be the best combination.

Identifiants

pubmed: 31164484
pii: respcare.06871
doi: 10.4187/respcare.06871
doi:

Substances chimiques

Oxygen S88TT14065

Types de publication

Evaluation Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1231-1239

Informations de copyright

Copyright © 2019 by Daedalus Enterprises.

Auteurs

Eugenio Garofalo (E)

Intensive Care Unit, University Hospital Mater Domini, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.

Andrea Bruni (A)

Intensive Care Unit, University Hospital Mater Domini, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.

Corrado Pelaia (C)

Intensive Care Unit, University Hospital Mater Domini, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.

Gianmaria Cammarota (G)

Anesthesia and Intensive Care, "Maggiore della Carità" Hospital, Novara, Italy.

Paolo Murabito (P)

Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

Eugenio Biamonte (E)

Intensive Care Unit, University Hospital Mater Domini, Catanzaro, Italy.

Karim Abdalla (K)

Intensive Care Unit, University Hospital Mater Domini, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.

Federico Longhini (F)

Intensive Care Unit, University Hospital Mater Domini, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy. longhini.federico@gmail.com.

Paolo Navalesi (P)

Intensive Care Unit, University Hospital Mater Domini, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.

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