Gene Expression Noise Produces Cell-to-Cell Heterogeneity in Eukaryotic Homologous Recombination Rate.
Saccharomyces cerevisiae
rate of evolution
recombination
single-cell analysis
stochastic gene expression
yeast
Journal
Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621
Informations de publication
Date de publication:
2019
2019
Historique:
received:
10
09
2018
accepted:
03
05
2019
entrez:
6
6
2019
pubmed:
6
6
2019
medline:
6
6
2019
Statut:
epublish
Résumé
Variation in gene expression among genetically identical individual cells (called gene expression noise) directly contributes to phenotypic diversity. Whether such variation can impact genome stability and lead to variation in genotype remains poorly explored. We addressed this question by investigating whether noise in the expression of genes affecting homologous recombination (HR) activity either directly (
Identifiants
pubmed: 31164905
doi: 10.3389/fgene.2019.00475
pmc: PMC6536703
doi:
Types de publication
Journal Article
Langues
eng
Pagination
475Références
Microbiol Mol Biol Rev. 1999 Jun;63(2):349-404
pubmed: 10357855
J Biol Chem. 2000 May 26;275(21):15895-904
pubmed: 10748203
Mol Cell Biol. 2001 Apr;21(7):2349-58
pubmed: 11259584
Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8263-9
pubmed: 11459962
Microbiol Mol Biol Rev. 2002 Dec;66(4):630-70, table of contents
pubmed: 12456786
Nature. 2003 Apr 10;422(6932):633-7
pubmed: 12687005
Nat Rev Genet. 2004 Jun;5(6):413-24
pubmed: 15153994
Mol Cell Biol. 2005 Aug;25(16):6948-55
pubmed: 16055708
Nat Genet. 2005 Sep;37(9):986-90
pubmed: 16086015
Science. 2005 Sep 23;309(5743):2010-3
pubmed: 16179466
Bioessays. 2005 Dec;27(12):1277-85
pubmed: 16299757
Genetics. 1992 Jun;131(2):261-76
pubmed: 1644271
Nature. 2006 Jun 15;441(7095):840-6
pubmed: 16699522
Nat Genet. 2006 Jun;38(6):636-43
pubmed: 16715097
Mol Cell. 2006 Dec 28;24(6):853-65
pubmed: 17189188
Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2797-802
pubmed: 17299042
Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3925-30
pubmed: 17360454
Proc Natl Acad Sci U S A. 2007 May 22;104(21):8935-40
pubmed: 17502621
Mol Microbiol. 2007 Nov;66(3):699-712
pubmed: 17919285
PLoS Genet. 2007 Dec;3(12):e228
pubmed: 18085829
Nature. 2008 Jul 17;454(7202):291-6
pubmed: 18633409
Mol Cancer Res. 2008 Nov;6(11):1710-7
pubmed: 19010819
Mol Microbiol. 2009 Mar;71(6):1333-40
pubmed: 19220745
Nature. 2009 Apr 9;458(7239):719-24
pubmed: 19360079
Genetics. 2009 Aug;182(4):1345-9
pubmed: 19535547
Nat Rev Genet. 2009 Aug;10(8):551-64
pubmed: 19597530
Genetics. 2010 Jun;185(2):395-404
pubmed: 20606014
J Mol Cell Biol. 2011 Feb;3(1):23-30
pubmed: 21278448
J Mol Cell Biol. 2011 Feb;3(1):51-8
pubmed: 21278452
PLoS Genet. 2011 Apr;7(4):e1001367
pubmed: 21533173
PLoS Genet. 2011 Apr;7(4):e1002057
pubmed: 21552543
Proteome Sci. 2011 Oct 04;9:62
pubmed: 21967861
Bioessays. 2012 Mar;34(3):170-3
pubmed: 22231918
PLoS Genet. 2012 Jan;8(1):e1002443
pubmed: 22275871
Cell. 2012 Jul 20;150(2):402-12
pubmed: 22817899
Science. 2012 Dec 21;338(6114):1627-30
pubmed: 23258895
Annu Rev Biochem. 2013;82:119-38
pubmed: 23451868
Proc Biol Sci. 2013 Jul 31;280(1767):20131104
pubmed: 23902900
PLoS Comput Biol. 2013;9(7):e1003161
pubmed: 23935476
Cell. 2013 Dec 19;155(7):1492-506
pubmed: 24360273
Cancer Res. 1988 Dec 1;48(23):6837-43
pubmed: 2460230
Front Genet. 2014 Jun 11;5:175
pubmed: 24966870
Genetics. 2014 Nov;198(3):795-835
pubmed: 25381364
Genome Biol Evol. 2015 Mar 11;7(4):969-84
pubmed: 25762217
G3 (Bethesda). 2015 Mar 30;5(6):1043-56
pubmed: 25823586
Mol Carcinog. 2016 May;55(5):953-63
pubmed: 26013599
Nat Rev Cancer. 2015 Aug;15(8):499-509
pubmed: 26156637
Cell. 1989 Feb 24;56(4):619-30
pubmed: 2645056
Yeast. 2016 Jun;33(6):209-16
pubmed: 26802744
Science. 2016 Mar 4;351(6277):1094-7
pubmed: 26941321
Oncotarget. 2016 Apr 26;7(17):23312-21
pubmed: 27004405
Trends Genet. 2016 Sep;32(9):566-575
pubmed: 27450436
Cell. 2016 Aug 25;166(5):1282-1294.e18
pubmed: 27545349
Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):9967-76
pubmed: 27551064
Genetics. 2016 Nov;204(3):975-986
pubmed: 27585847
Mol Biol Evol. 2017 Feb 1;34(2):419-436
pubmed: 27836985
Int J Cancer. 2017 Jun 1;140(11):2408-2413
pubmed: 28052327
Eur J Cell Biol. 2017 Mar;96(2):206-217
pubmed: 28258766
PLoS Biol. 2017 May 9;15(5):e2000644
pubmed: 28486496
Nucleic Acids Res. 2018 Jun 20;46(11):5634-5650
pubmed: 29741650
Elife. 2018 Aug 20;7:
pubmed: 30124429
Science. 1995 Jul 14;269(5221):238-40
pubmed: 7618086
Genetics. 1994 Nov;138(3):587-95
pubmed: 7851757
J Biol Chem. 1995 Mar 3;270(9):4193-6
pubmed: 7876174
Cell. 1997 Jan 24;88(2):253-63
pubmed: 9008166
Nature. 1998 Jan 22;391(6665):407-10
pubmed: 9450760
Mol Cell Biol. 1998 May;18(5):2779-88
pubmed: 9566897
Nucleic Acids Res. 1998 Dec 15;26(24):5589-95
pubmed: 9837987