Stereotactic radiation therapy in oligometastatic colorectal cancer: outcome of 102 patients and 150 lesions.


Journal

Clinical & experimental metastasis
ISSN: 1573-7276
Titre abrégé: Clin Exp Metastasis
Pays: Netherlands
ID NLM: 8409970

Informations de publication

Date de publication:
08 2019
Historique:
received: 03 01 2019
accepted: 29 05 2019
pubmed: 6 6 2019
medline: 24 3 2020
entrez: 6 6 2019
Statut: ppublish

Résumé

To evaluate the local control (LC), progression free survival (PFS), out-field PFS, overall survival (OS), toxicity and failure predictors of SRT in a series of various sites oligometastatic CRC patients. Patients with oligometastatic CRC disease were analyzed retrospectively. The SRT prescribed dose was dependent on the lesion volume and its location. 102 consecutive oligometastatic CRC patients (150 lesions) were included. They underwent SRT between 2012 and 2015. Median prescription dose was 45 Gy (median dose/fraction was 15 Gy/3 fractions biological equivalent dose (BED

Identifiants

pubmed: 31165360
doi: 10.1007/s10585-019-09976-z
pii: 10.1007/s10585-019-09976-z
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

331-342

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Auteurs

V Dell'Acqua (V)

Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

A Surgo (A)

Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

F Kraja (F)

Division of Oncology, University Hospital Centre "Mother Theresa", Rruga e Dibrës 372, 1000, Tirana, Albania.

J Kobiela (J)

Department of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Marii Skłodowskiej-Curie 3a, 80-210, Gdańsk, Poland.

Maria Alessia Zerella (MA)

Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy. mariaalessia.zerella@ieo.it.
Department of Oncology and Hemato-Oncology, University of Milan, Via Festa del Perdono 7, 20122, Milan, Italy. mariaalessia.zerella@ieo.it.

P Spychalski (P)

Department of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Marii Skłodowskiej-Curie 3a, 80-210, Gdańsk, Poland.

S Gandini (S)

Group Leader Department of Experimental Oncology, European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

C M Francia (CM)

Palliative Care and Pain Therapy Unit, European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

D Ciardo (D)

Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

C Fodor (C)

Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

A M Ferrari (AM)

Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

G Piperno (G)

Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

F Cattani (F)

Unit of Medical Physics, European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

S Vigorito (S)

Unit of Medical Physics, European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

F Pansini (F)

Unit of Medical Physics, European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

W Petz (W)

Division of Gastrointestinal Surgery, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy.

R Orecchia (R)

Scientific Directorate, European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

M C Leonardi (MC)

Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.

B A Jereczek-Fossa (BA)

Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141, Milan, Italy.
Department of Oncology and Hemato-Oncology, University of Milan, Via Festa del Perdono 7, 20122, Milan, Italy.

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