Development of Ionic Liquid-Water-Based Thermomorphic Solvent (TMS)-Systems for Biocatalytic Reactions.
enzymes
ionic liquids
lipases
recycling
thermomorphic solvent (TMS)-systems
two-phase system
Journal
Biotechnology journal
ISSN: 1860-7314
Titre abrégé: Biotechnol J
Pays: Germany
ID NLM: 101265833
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
21
05
2019
pubmed:
6
6
2019
medline:
11
2
2020
entrez:
6
6
2019
Statut:
ppublish
Résumé
The applicability of ionic liquid-water-based thermomorphic solvent (TMS)-systems with an upper critical solution temperature for homogeneous biocatalysis is investigated. Cholinium- and imidazolium-based ionic liquids are used to facilitate a temperature-dependent phase change, which can be easily fine-tuned by adding salts or polar organic solvents. Within the TMS-system, a high enzymatic activity and subsequent full conversion is achieved in the intermittent monophasic reaction system of the TMS-system. Therefore, the biocatalyst can be easily recycled after separating the phases at lower temperatures.
Identifiants
pubmed: 31166077
doi: 10.1002/biot.201900215
doi:
Substances chimiques
Ionic Liquids
0
Solvents
0
Water
059QF0KO0R
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e1900215Subventions
Organisme : Leibniz ScienceCampus Phosphorus Research Rostock
Organisme : Deutsche Forschungsgemeinschaft
ID : KR 2491/11-1
Organisme : Bundesministerium für Bildung und Forschung
ID : 031A123
Organisme : German Federal Ministry of Education and Research
ID : 031A123
Organisme : DFG
ID : KR 2491/11-1
Informations de copyright
© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.