Influence of the Assembly State on the Functionality of a Supramolecular Jagged1-Mimicking Peptide Additive.
Journal
ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658
Informations de publication
Date de publication:
31 May 2019
31 May 2019
Historique:
received:
03
04
2019
accepted:
18
04
2019
entrez:
8
6
2019
pubmed:
7
6
2019
medline:
7
6
2019
Statut:
ppublish
Résumé
Expanding the bioactivation toolbox of supramolecular materials is of utmost relevance for their broad applicability in regenerative medicines. This study explores the functionality of a peptide mimic of the Notch ligand Jagged1 in a supramolecular system that is based on hydrogen bonding ureido-pyrimidinone (UPy) units. The functionality of the peptide is studied when formulated as an additive in a supramolecular solid material and as a self-assembled system in solution. UPy conjugation of the DSL
Identifiants
pubmed: 31172036
doi: 10.1021/acsomega.9b00869
pmc: PMC6545632
doi:
Types de publication
Journal Article
Langues
eng
Pagination
8178-8187Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
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