Towards OPM-MEG in a virtual reality environment.
Journal
NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515
Informations de publication
Date de publication:
01 10 2019
01 10 2019
Historique:
received:
19
02
2019
revised:
12
04
2019
accepted:
03
06
2019
pubmed:
8
6
2019
medline:
28
2
2020
entrez:
8
6
2019
Statut:
ppublish
Résumé
Virtual reality (VR) provides an immersive environment in which a participant can experience a feeling of presence in a virtual world. Such environments generate strong emotional and physical responses and have been used for wide-ranging applications. The ability to collect functional neuroimaging data whilst a participant is immersed in VR would represent a step change for experimental paradigms; unfortunately, traditional brain imaging requires participants to remain still, limiting the scope of naturalistic interaction within VR. Recently however, a new type of magnetoencephalography (MEG) device has been developed, that employs scalp-mounted optically-pumped magnetometers (OPMs) to measure brain electrophysiology. Lightweight OPMs, coupled with precise control of the background magnetic field, enables participant movement during data acquisition. Here, we exploit this technology to acquire MEG data whilst a participant uses a virtual reality head-mounted display (VRHMD). We show that, despite increased magnetic interference from the VRHMD, we were able to measure modulation of alpha-band oscillations, and the visual evoked field. Moreover, in a VR experiment in which a participant had to move their head to look around a virtual wall and view a visual stimulus, we showed that the measured MEG signals map spatially in accordance with the known organisation of primary visual cortex. This technique could transform the type of neuroscientific experiment that can be undertaken using functional neuroimaging.
Identifiants
pubmed: 31173906
pii: S1053-8119(19)30495-1
doi: 10.1016/j.neuroimage.2019.06.010
pmc: PMC8276767
mid: NIHMS1710582
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
408-417Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 203257/Z/16/Z
Pays : United Kingdom
Organisme : NIMH NIH HHS
ID : R44 MH110288
Pays : United States
Informations de copyright
Copyright © 2019. Published by Elsevier Inc.
Références
Neuroimage. 2018 Nov 1;181:831-844
pubmed: 29960087
J Anxiety Disord. 2019 Jan;61:27-36
pubmed: 30287083
Phys Med Biol. 2017 Nov 10;62(23):8909-8923
pubmed: 29035875
Nature. 2003 Apr 10;422(6932):596-9
pubmed: 12686995
PLoS One. 2016 Aug 26;11(8):e0157655
pubmed: 27564416
Phys Med Biol. 2015 Nov 7;60(21):R271-95
pubmed: 26447925
Neuroimage. 2018 Nov 1;181:760-774
pubmed: 30031934
Neuroimage. 2017 Feb 1;146:667-678
pubmed: 27639354
Front Hum Neurosci. 2013 Apr 15;7:138
pubmed: 23596409
Neuroimage. 2019 Jul 1;194:244-258
pubmed: 30885786
Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16783-8
pubmed: 21930901
Science. 1968 Aug 23;161(3843):784-6
pubmed: 5663803
Neuroimage. 2018 Nov 1;181:513-520
pubmed: 30016678
Sci Rep. 2019 Apr 2;9(1):5490
pubmed: 30940844
Elife. 2014 Mar 25;3:e01867
pubmed: 24668169
Phys Med Biol. 2013 Sep 7;58(17):6065-77
pubmed: 23939051
Behav Res Methods. 2018 Apr;50(2):862-869
pubmed: 28550656
IEEE Trans Biomed Eng. 1997 Sep;44(9):867-80
pubmed: 9282479
J Neurol Sci. 1998 Apr 1;156(2):186-94
pubmed: 9588856
J Neurosci Methods. 2017 Jan 30;276:38-45
pubmed: 27887969
Biomed Opt Express. 2012 May 1;3(5):981-90
pubmed: 22567591
Neuroimage. 2017 Jul 15;155:565-576
pubmed: 27903441
Neuroimage. 2008 Feb 15;39(4):1788-802
pubmed: 18155612
Br J Psychol. 2018 Aug;109(3):395-417
pubmed: 29504117
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):694-9
pubmed: 11209067
Front Psychol. 2019 Feb 06;10:173
pubmed: 30787898
Neuroimage. 2017 Apr 1;149:404-414
pubmed: 28131890
Nature. 2018 Mar 29;555(7698):657-661
pubmed: 29562238
Nat Neurosci. 2017 Feb 23;20(3):327-339
pubmed: 28230841
Phys Med Biol. 1987 Jan;32(1):11-22
pubmed: 3823129
Neuroimage. 2017 Feb 15;147:542-553
pubmed: 28007515